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Veletri (epoprostenol) - Analysis and Forecasts from 2010 to 2020

Published By :

GlobalData

Published Date : Jul 2011

Category :

Therapeutic Area

No. of Pages : 37 Pages


GlobalDatas pharmaceuticals report, Veletri (epoprostenol) Analysis and Forecasts from 2010 to 2020 provides Veletri sales estimates for US, EU5 and Japan. In addition, it covers detailed clinical assessment of the drug, factors impacting drug sales, competitive landscape, and analysis of sales performance during the forecast period (2010-2020). The report also includes information on Pulmonary Arterial Hypertension market. This report is built using data and information sourced from GlobalDatas proprietary databases, primary and secondary research using Companys corporate website, SEC filings, investor presentations and featured press releases, both from company and industry-specific third party sources, put together with in-house analysis, by GlobalData's team of industry experts. 

Scope

  • Therapy area profile including patient population for the US, EU5 and Japan (seven major markets)
  • Analysis and review of Veletri including historical sales data
  • Qualitative and quantitative assessment of market space
  • Analysis of the trends, drivers and restraints shaping and defining the markets
  • In-depth analysis of Veletri including efficacy, safety, pricing, competition and other details which influence its sales potential
  • Detailed sales forecast for 2010-2020 for Veletri in the seven major markets
Reasons to buy

  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of competition by understanding the changing competitive landscape
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of the drugs performance 
  • Examine the historical sales performance of a drug in seven major markets
  • Obtain sales forecast for currently marketed/pipeline drug for 2011-2020 for all seven major markets
Table of Content

1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 3
1.2 List of Figures 3

2 Introduction 4
2.1 Pulmonary Arterial Hypertension 4
2.2 Epidemiology 4
2.2.1 Prevalence 4
2.2.2 Mortality 5
2.3 Etiology 5
2.3.1 Scleroderma 5
2.3.2 Sickle Cell Disease 5
2.3.3 HIV/AIDS 5
2.3.4 Drug Abuse and Toxins 5
2.4 Economic Impact of PAH 5
2.5 GlobalData Report Guidance 6

3 Pulmonary Arterial Hypertension (PAH): Market Characterization 7
3.1 PAH Market 7
3.2 PAH Market Forecasts and CAGR 8
3.3 PAH Market : Drivers and Restraints 9
3.3.1 Drivers 9
3.3.2 Barriers 10

4 Classification of PAH 11
4.1 Classification Based on Cause and Clinical Presentation 11
4.1.1 Idiopathic PAH 11
4.1.2 Familial PAH 11
4.1.3 Drug Induced PAH 11
4.1.4 PAH Associated with Other Conditions 11
4.1.5 PAH Associated with Significant Venous or Capillary Involvement 11
4.2 Symptomatic Profile of PAH 11

5 Evolution of PAH Treatments 12

6 Medications 13
6.1 Prostanoids 13
6.1.1 Epoprostenol 13
6.1.2 Treprostinil 13
6.1.3 Iloprost 13
6.1.4 Beraprost 13
6.2 Endothelin Receptor Antagonists 13
6.2.1 Bosentan 13
6.2.2 Ambrisentan 14
6.2.3 Sitaxsentan 14
6.3 Phosphodiesterase Type 5 Inhibitors 14
6.3.1 Sildenafil 14
6.3.2 Tadalafil 14
6.4 Surgical Treatments 14
6.5 Investigational Combination Regimens 15
6.6 New Targets for PAH Therapy 15

7 Market Share by Class in PAH 17

8 Veletri (epoprostenol) 18
8.1 Introduction 18
8.2 Mechanism of Action 18
8.3 Clinical Studies 18
8.4 Approval History of Veletri 19
8.5 Factors Affecting Sales of Veletri 19
8.5.1 More Convenient Administration 19
8.5.2 Flexible Reconstitution (dissolving) Options 19
8.5.3 Advantages of Veletri over Flolan 19
8.5.4 Efficacy Profile 19
8.6 Drug Evaluation 19
8.6.1 Drug Risk Benefit Score 19
8.6.2 Intensity of Competition 21
8.7 Sales Estimates 21
8.7.1 Target Patient Pool of Veletri 21
8.7.2 Dosing 22
8.7.3 Market Penetration 22
8.7.4 Annual Cost of Therapy 22
8.7.5 Sales Projections of Veletri 23

9 PAH Market: Appendix 32
9.1 Market Definitions 32
9.2 List of Abberiviations 32
9.3 Research Methodology 33
9.3.1 Coverage 33
9.3.2 Secondary Research 33
9.3.3 Forecasting 33
9.3.4 Number of Patients Approved to take the Drug 34
9.3.5 Net Penetration of Drug 34
9.3.6 Net Annual Dosing 35
9.3.7 Annual Cost of Therapy 35
9.3.8 Primary Research 35
9.3.9 Expert Panels 35
9.4 Drug Sales Estimates Model 35
9.5 Contact Us 36
9.6 Disclaimer 36
9.7 Sources 36

List of Table


Table 1: PAH, Global, Major Marketed Drugs 7
Table 2: PAH, Global, Pipeline (PhaseIII) 8
Table 3: PAH Drugs Evolution 12
Table 4: Hemodynamics During Chronic Administration of epoprostenol in Patients with PPH 18
Table 5: Drug Risk Benefit Score of Veletri 20
Table 6: Efficacy Comparison of Veletri with its Competitors 20
Table 7: Veletri, PAH, Global, Sales Estimates ($m), 20102020 23
Table 8: Veletri, PAH, The US, Sales Estimates ($m), 20102020 24
Table 9: Veletri, PAH, The UK, Sales Estimates ($m), 20122020 25
Table 10: Veletri, PAH, France, Sales Estimates ($m), 20122020 26
Table 11: Veletri, PAH, Germany, Sales Estimates ($m), 20122020 27
Table 12: Veletri, PAH, Italy, Sales Estimates ($m), 20122020 28
Table 13: Veletri, PAH, Spain, Sales Estimates ($m), 20122020 29
Table 14: Veletri, PAH, Japan, Sales Estimates ($m), 20122020 30

List of Chart


Figure 1: PAH, Global, Market Size Forecasts ($bn), 20102020 8
Figure 2: PAH, Worldwide, Market Share by Class (%), 2010 17
Figure 3: Drug Model Diagram of Veletri 21
Figure 4: Veletri, PAH, Global, Sales Estimates ($m), 20102020 23
Figure 5: Veletri, PAH, The US, Sales Estimates ($m), 20102020 24
Figure 6: Veletri, PAH, The UK, Sales Estimates ($m), 20122020 25
Figure 7: Veletri, PAH, France, Sales Estimates ($m), 20122020 26
Figure 8: Veletri, PAH, Germany, Sales Estimates ($m), 20122020 27
Figure 9: Veletri, PAH, Italy, Sales Estimates ($m), 20122020 28
Figure 10: Veletri, PAH, Spain, Sales Estimates ($m), 20122020 29
Figure 11: Veletri, PAH, Japan, Sales Estimates ($m), 20122020 30
Figure 12: Veletri, PAH, Global, Sales Distribution by Country (%), 2020 31
Figure 13: Drug Model Diagram 34
Figure 14: Patients Approved for the Drug 35

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