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Stalevo Analysis and Estimates from 2003 to 2020

Published By :

GlobalData

Published Date : Jul 2011

Category :

Therapeutic Area

No. of Pages : 38 Pages



GlobalDatas pharmaceuticals report, Stalevo Analysis and Estimates from 2003 to 2020 provides Stalevo sales estimates for US, EU5 and Japan. In addition, it covers detailed clinical assessment of the drug, factors impacting drug sales, competitive landscape, and analysis of sales performance during the forecast period (2003-2020). The report also includes information on Parkinson's Disease market. This report is built using data and information sourced from GlobalDatas proprietary databases, primary and secondary research using Companys corporate website, SEC filings, investor presentations and featured press releases, both from company and industry-specific third party sources, put together with in-house analysis, by GlobalData's team of industry experts. 

Scope
  • Therapy area profile including patient population for the US, EU5 and Japan (seven major markets)
  • Analysis and review of Stalevo including historical sales data
  • Qualitative and quantitative assessment of market space
  • Analysis of the trends, drivers and restraints shaping and defining the markets
  • In-depth analysis of Stalevo including efficacy, safety, pricing, competition and other details which influence its sales potential
  • Detailed sales forecast for 2011-2020 for Stalevo in each of the seven major markets
Reasons to buy
  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of competition by understanding the changing competitive landscape
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of the drugs performance 
  • Examine the historical sales performance of a drug in seven major markets
  • Obtain sales forecast for currently marketed/pipeline drug for 2011-2020 for all seven major markets
Table of content

1 Table of contents
1 Table of contents 2
1.1 List of Tables 3
1.2 List of Figures 4

2 Introduction 5
2.1 Parkinsons Disease 5
2.2 Symptoms of Parkinsons Disease 5
2.3 Diagnosis of Parkinsons Disease 6
2.4 Parkinsons Disease Treatment Strategies 6
2.5 Parkinsons Disease Market 7
2.6 Epidemiology 7
2.7 Parkinsons Disease by Age and Gender 7
2.8 Etiology 8
2.9 GlobalData Report Guidance 9

3 Parkinsons Disease: Market Characterization 10
3.1 Parkinsons Disease Market 10
3.2 Parkinsons Disease Market Forecasts and CAGR 10
3.3 Factors Affecting Parkinsons Disease Market 11
3.3.1 High Prevalence: Parkinsons Disease is the Second Most Frequent Neurodegenerative Disorder 11
3.3.2 Increase in Old Age Population 11
3.3.3 Patent Expiry of Prominent Drugs 11

4 Stages of Parkinsons Disease and Comparison of Treatments 12
4.1 The Hoehn and Yahr Scale 12
4.2 Modified Hoehn and Yahr Scale 12
4.3 The UPDRS 13

5 Staging of Parkinsons Disease 16
5.1 Distribution of Parkinsons Disease Patients by Age Groups 16
5.2 Distribution of Patients by Stages 16

6 Stalevo 17
6.1 Introduction 17
6.2 Mechanism of Action 17
6.3 Clinical Studies 17
6.4 Approval History of Stalevo 19
6.5 Factors Affecting Sales of Stalevo 19
6.5.1 Combination of Two Drugs 19
6.5.2 Prostate Cancer and Cardiovascular Risk 20
6.5.3 Generics Entry 20
6.5.4 Greater Dosing Flexibility 20
6.6 Drug Evaluation 21
6.6.1 Drug Risk Benefit Score 21
6.6.2 Intensity of Competition 22
6.7 Sales Estimates 23
6.7.1 Target Patient Pool of Stalevo 23
6.7.2 Dosing 24
6.7.3 Market Penetration 24
6.7.4 Annual Cost of Therapy 24
6.7.5 Sales Estimates of Stalevo 25

7 Parkinson Disease Market: Appendix 34
7.1 Market Definitions 34
7.2 List of Abberiviations 34
7.3 Research Methodology 34
7.3.1 Coverage 34
7.3.2 Secondary Research 35
7.3.3 Forecasting 35
7.3.4 Number of Patients Approved to take the Drug 35
7.3.5 Net Penetration of Drug 35
7.3.6 Net Annual Dosing 36
7.3.7 Annual Cost of Therapy 36
7.3.8 Primary Research 36
7.3.9 Expert Panels 37
7.4 Drug Sales Estimates Model 37
7.5 Contact Us 37
7.6 Disclaimer 38
7.7 Sources 38

List of Table


Table 1: Clinical Motor and Nonmotor Features of Parkinsons Disease 5
Table 2: Hoehn and Yahr Stages of Parkinsons Disease 12
Table 3: Hoehn and Yahr Stages of Parkinsons Disease 12
Table 4: Four Items, Part 1 of UPDRS 13
Table 5: Thirteen Items, Part 2 of UPDRS 13
Table 6: Fourteen Items, Part 3 of UPDRS 14
Table 7: Fourteen Items, Part 3 of UPDRS 14
Table 8: Distribution of Parkinsons Patients According to Hoehn and Yahr Classification 16
Table 9: Nordic Study Primary Measures 18
Table 10: Nordic Study Secondary Measures 18
Table 11: German-Austrian Study Primary Measures 18
Table 12: German-Austrian Study Secondary Measures 19
Table 13: Approval History of Stalevo 19
Table 14: Drug Risk Benefit Score of Stalevo 21
Table 15: Efficacy Comparison 21
Table 16: Efficacy Parameters 22
Table 17: Annual Cost of Therapy, 2011 24
Table 18: Stalevo, Parkinsons Disease, Global, Sales Estimates ($m), 20032020 25
Table 19: Stalevo, Parkinsons Disease, The US, Sales Estimates ($m), 20032020 26
Table 20: Stalevo, Parkinsons Disease, The UK, Sales Estimates ($m), 20032020 27
Table 21: Stalevo, Parkinsons Disease, France, Sales Estimates ($m), 20032020 28
Table 22: Stalevo, Parkinsons Disease, Germany, Sales Estimates ($m), 20032020 29
Table 23: Stalevo, Parkinsons Disease, Italy, Sales Estimates ($m), 20032020 30
Table 24: Stalevo, Parkinsons Disease, Spain, Sales Estimates ($m), 20032020 31
Table 25: Stalevo, Parkinsons Disease, Japan, Sales Estimates ($m), 20132020 32

List of Chart


Figure 1: Current Pharmacologic Therapies for Parkinsons disease and Their Potential Sites of Action in the CNS 6
Figure 2: The Age-Specific Prevalence Rates of Parkinsons Disease in the Elderly Among Five European Countries, 2003 8
Figure 3: Parkinsons Disease, Global, Market Size Estimates ($bn), 20102020 10
Figure 4: Proportion of Population 60 Years or Older, World, 1950-2050 11
Figure 5: Points Distribution of UPDRS 15
Figure 6: Distribution of Parkinsons Disease Patients by Hoehn & Yahr Classification 16
Figure 7: Drug Model Diagram of Stalevo 23
Figure 8: Stalevo, Parkinsons Disease, Global, Sales Estimates ($m), 20032020 25
Figure 9: Stalevo, Parkinsons Disease, The US, Sales Estimates ($m), 20032020 26
Figure 10: Stalevo, Parkinsons Disease, The UK, Sales Estimates ($m), 20032020 27
Figure 11: Stalevo, Parkinsons Disease, France, Sales Estimates ($m), 20032020 28
Figure 12: Stalevo, Parkinsons Disease, Germany, Sales Estimates ($m), 20032020 29
Figure 13: Stalevo, Parkinsons Disease, Italy, Sales Estimates ($m), 20032020 30
Figure 14: Stalevo, Parkinsons Disease, Spain, Sales Estimates ($m), 20032020 31
Figure 15: Stalevo, Parkinsons Disease, Japan, Sales Forecasts ($m), 20132020 32
Figure 16: Stalevo, Parkinsons Disease, Sales Distribution by Country (%), 2013 33
Figure 17: Drug Model Diagram 36
Figure 18: Patients Approved for the Drug 36

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