Proteins C & S Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 - 2025

Proteins C & S Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 - 2025

  • Transparency Market Research
  • Ongoing
  • Pharmaceutical

Report Description

Protein C is a vitamin K-dependent glycoprotein produced in the liver and circulated in blood as an inactive enzyme precursor. In order to get itself activated, protein C binds to endothelial proteoglycan thrombomodulin, generally catalyzed by thrombin. The anticoagulant activity by activated protein C is exerted primarily through inactivation of coagulation factors viz. VIIIa and Va, which are required for activation of factor X and production of thrombin. The catalytic activity of the activated protein C requires assistance of protein S, a vitamin K-dependent co-factor. Protein S assists protein C in the inactivation of coagulation factors viz. Va and VIIIa. The half-life of protein C is eight hours and that of protein S is 30 hours.

 Lack of activated protein C interrupts and disturbs the equilibrium between procoagulant and anticoagulant proteins and stimulates a prothrombotic environment. Apart from maintaining balance or equilibrium, activated protein C helps in maintaining an appropriate flow of the venous circulation with prolonged exposure of platelet phospholipids and procoagulant proteins. Statistically, the protein C deficiency occurs in approximately one in every 200–500 individuals, whereas the protein S deficiency is found in approximately one in every 20,000 individuals. The disease caused by the absence of any of the natural anticoagulants leads to thrombophilia. The absence or low level of natural anticoagulants is either due to hereditary defects; or acquired out of circumstances such as surgery, cancer; or due to certain contraceptives and menopausal hormone replacement products.

 Diagnosis of the deficiency of proteins C and S is generally carried out with the help of blood tests conducted to measure the level and activity of natural anticoagulants. The blood test is recommended to be conducted at least 3–4 weeks after discontinuation of medicines such as heparin or warfarin. Several physicians and health care experts suggest repeat test, as abnormal or false results are very common in case of this test. This may be because of pregnancy or presence of birth control pills demonstrating a reduced level of protein C or S. Recent studies have shown that proteins C and S may induce chances of acquiring arterial blood clots in people aged 55 years or below. Major drivers for the market include growing awareness among people with respect to genetic defects and increasing trend of regular health checkups in developed countries. Major restraints for the proteins C & S market include possible anxiety regarding the diagnosis that never shows symptoms and lack of insurance coverage.

Geographically, the global proteins C & S market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The market in North America is expected to expand during the forecast period, followed by Europe. Growth of the market in North America is attributable to increase in demand for advanced treatments, rise in health care expenditure, and high diagnosis rate. Asia Pacific is an emerging market due to developing health care infrastructure, increasing government expenditure, growing patient awareness, and rising number of patients suffering from deficiency of proteins C and S. However, lack of insurance coverage, limited access to health care facilities, and lack of patient education are restraining the proteins C & S market in regions such as Middle East & Africa and Latin America. 

Some of the major companies operating in the proteins C & S market are Baxter International Inc., Abbott Laboratories, Trinity Biotech, Siemens AG, Zycare, Inc. Becton, Dickinson and Company, and Sienco Co., Ltd.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market 

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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