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Published on : Jun 06, 2017

Albany, New York, June 06, 2017: This research report provides a comprehensive overview of the women’s health pipeline landscape across the world. The three disorders extensively covered in this report are polycystic ovarian syndrome, female infertility, and endometriosis. The report reviews the primary pipeline products by profiling drugs along with their description, MoA and development, and details regarding licensing, collaboration, and other developmental activities. 

It profiles prominent players involved in the discovery and development of drugs and therapies for the treatment of the aforementioned disorders and offers insights into all their latest developments, projects, and deals. It also sheds light on pipeline products based on different stages of development, ranging from pre-registration to discovery and undisclosed stages. For a clear understanding, the pipeline is also explained in terms of MoA, target, route of administration, and type of molecule. A summary of all the dormant and discontinued pipeline projects also forms a vital part of the report.

The three disorders are largely caused by dysfunction of the endocrine system. However, with changing lifestyles, there is a broad range of factors. The increasing prevalence of infertility is one of the primary factors escalating the development of the women health cluster drug pipeline. Infertility can be defined as the inability to conceive children or young ones within 12 months of unprotected sexual intercourse. There are several reasons behind female infertility, including aging, irregular menstrual cycles, damage to fallopian tubes, cervical causes, hormonal causes, uterine causes, STDs, and genetic causes. 

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Polycystic ovary syndrome (PCOS) is among the common hormonal disorders happening to women belonging to reproductive age group. Some of the common symptoms of PCOS are acne, menstrual abnormality, hair fall, weight gain, facial hair growth, and polycystic ovaries. The occurrence of this syndrome is often attributed to genetic causes. 

Endometriosis is a condition in which tissues that normally line inside of the uterus (endometrium) grow outside the uterus. Symptoms of this condition may include menstrual cramps, pelvic pain, inflammation, painful bowel, painful intercourse, and abnormal bleeding. Both PCOS and endometriosis can have infertility as one of the symptoms.
 
Extensive research activities are going on all around the world for the development effective treatments for these conditions. Currently, the treatment pipeline for these disorders ranges from 12 in PCOS to 87 in female infertility. Most of the therapies in the development phase act on hormone receptors, pointing at the hormone-driven pathophysiology of these diseases. However, especially in polycystic ovarian syndrome, a wider range of molecular targets, such as chemokine receptors, intracellular protein kinases, and other cell signaling components are under development.

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