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Pharmacogenomic Partnering Terms and Agreements

Published By :

Current Partnering

Published Date : Apr 2011

Category :


No. of Pages : 273 Pages

The Pharmacogenomic Partnering Terms and Agreements report provides comprehensive understanding and unprecedented access to the pharmacogenomic partnering deals and agreements entered into by the worlds leading healthcare companies.

The report provides a detailed understanding and analysis of how and why companies enter pharmacogenomic partnering deals. The majority of deals are discovery or development stage whereby the licensee obtains a right or an option right to license the licensors pharmacogenomic technology. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes.

Understanding the flexibility of a prospective partner’s negotiated deals terms provides critical insight into the negotiation process in terms of what you can expect to achieve during the negotiation of terms. Whilst many smaller companies will be seeking details of the payments clauses, the devil is in the detail in terms of how payments are triggered - contract documents provide this insight where press releases do not.

This report contains over 500 links to online copies of actual pharmacogenomic deals and contract documents as submitted to the Securities Exchange Commission by companies and their partners. Contract documents provide the answers to numerous questions about a prospective partner’s flexibility on a wide range of important issues, many of which will have a significant impact on each party’s ability to derive value from the deal.

The initial chapters of this report provide an orientation of pharmacogenomic dealmaking and business activities. 

Chapter 1 provides an introduction to the report, whilst 

Chapter 2 provides an overview of the trends in pharmacogenomic dealmaking since 2005, including details of average headline, upfront, milestone and royalty terms.

Chapter 3 provides a review of the leading pharmacogenomic deals since 2005. Deals are listed by headline value, signed by bigpharma, most active bigpharma, and most active of all biopharma companies. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 4 provides a comprehensive listing of the top 50 bigpharma companies with a brief summary followed by a comprehensive listing of pharmacogenomic deals as well as contract documents available in the public domain. Where available, each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 5 provides a comprehensive and detailed review of pharmacogenomic partnering deals signed and announced since 2005, where a contract document is available in the public domain. The chapter is organized by company A-Z, stage of development at signing, deal type (collaborative R&D, co-promotion, licensing etc), and specific therapy focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.

The report also includes numerous tables and figures that illustrate the trends and activities in pharmacogenomic partnering and dealmaking since 2005.

In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of pharmacogenomic technologies and products.

Additional Information

Key benefits Pharmacogenomic Partnering Terms and Agreements provides the reader with the following key benefits:

  • In-depth understanding of pharmacogenomic deal trends since 2005
  • Access to headline, upfront, milestone and royalty data
  • Analysis of the structure of pharmacogenomic agreements with numerous real life case studies
  • Comprehensive access to over 500 actual pharmacogenomic contracts entered into by the world’s biopharma companies
  • Detailed access to actual pharmacogenomic contracts enter into by the leading fifty bigpharma companies
  • Insight into the terms included in a pharmacogenomic agreement, together with real world clause examples
  • Understand the key deal terms companies have agreed in previous deals
  • Undertake due diligence to assess suitability of your proposed deal terms for partner companies
  • Report scope Pharmacogenomic Partnering Terms and Agreements is intended to provide the reader with an in-depth understanding and access to pharmacogenomic trends and structure of deals entered into by leading companies worldwide.
Pharmacogenomic Partnering Terms and Agreements includes:

  • Trends in pharmacogenomic dealmaking in the biopharma industry since 2005
  • Analysis of pharmacogenomic deal structure
  • Access to headline, upfront, milestone and royalty data
  • Case studies of real-life pharmacogenomic deals
  • Access to over 500 pharmacogenomic contract documents
  • The leading pharmacogenomic deals by value since 2005
  • Most active pharmacogenomic dealmakers since 2005
  • The leading pharmacogenomic partnering resources
In Pharmacogenomic Partnering Terms and Agreements, the available contracts are listed by:

  • Company A-Z
  • Headline value
  • Stage of development at signing
  • Deal component type
  • Specific therapy target
  • Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each contract document on demand.
The Pharmacogenomic Partnering Terms and Agreements report provides comprehensive access to available deals and contract documents for over 500 pharmacogenomic deals. Analyzing actual contract agreements allows assessment of the following:

  • What are the precise pharmacogenomic rights granted or optioned?
  • What is actually granted by the agreement to the partner company?
  • What exclusivity is granted?
  • What is the payment structure for the deal?
  • How are sales and payments audited?
  • What is the deal term?
  • How are the key terms of the agreement defined?
  • How are IPRs handled and owned?
  • Who is responsible for commercialization?
  • Who is responsible for development, supply, and manufacture?
  • How is confidentiality and publication managed?
  • How are disputes to be resolved?
  • Under what conditions can the deal be terminated?
  • What happens when there is a change of ownership?
  • What sublicensing and subcontracting provisions have been agreed?
  • Which boilerplate clauses does the company insist upon?
  • Which boilerplate clauses appear to differ from partner to partner or deal type to deal type?
  • Which jurisdiction does the company insist upon for agreement law?
Table Of Content

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in pharmacogenomic dealmaking
2.1. Introduction
2.2. Pharmacogenomic partnering over the years
2.3. Bigpharma pharmacogenomic dealmaking activity
2.4. Bigpharma not active in pharmacogenomics
2.5. Pharmacogenomic partnering by deal type
2.6. Pharmacogenomic partnering by disease type
2.7 Average deal terms for pharmacogenomics
2.7.1 Pharmacogenomic headline values
2.7.2 Pharmacogenomic upfront payments
2.7.3 Pharmacogenomic milestone payments
2.7.4 Pharmacogenomic royalty rates

Chapter 3 - Leading pharmacogenomic deals
3.1. Introduction
3.2. Top pharmacogenomic deals by value
3.3. Top pharmacogenomic deals involving bigpharma

Chapter 4 - Bigpharma pharmacogenomic deals
4.1. Introduction
4.2. How to use bigpharma pharmacogenomic partnering deals
4.3. Bigpharma pharmacogenomic partnering company profiles
Alcon Labs
Baxter International
Biogen Idec
Boehringer Ingelheim
Bristol-Myers Squibb
Daiichi Sankyo
Dainippon Sumitomo
Eli Lilly
Forest Laboratories
Gilead Sciences
Johnson & Johnson
Kyowa Hakko Kirin
Merck & Co
Merck KGaA
Mitsubishi Tanabe
Novo Nordisk
Nycomed Pharma

Chapter 5 - Pharmacogenomic dealmaking directory
5.1. Introduction
5.2. Company A-Z
5.3. By stage of development
Phase I
Phase II
Phase III
5.4. By deal type
Asset and product purchase
Collaborative R&D
Joint venture
5.5. By therapy area
Hospital care
Central nervous system
Genetic disorders
Genetic disorders
Sensory organ
Animal health

Chapter 6 - Pharmacogenomic partnering resource center
6.1. Online pharmacogenomic partnering
6.2. Pharmacogenomic partnering events
6.3. Further reading on pharmacogenomic dealmaking


Appendix 1 - Deal type definitions

Appendix 2 - Example pharmacogenomic partnering agreement
About Wildwood Ventures

List of Chart

Figure 1: Pharmacogenomic partnering since 2005
Figure 2: Bigpharma - top 50 - pharmacogenomic deals 2005 to 2010
Figure 3: Inactive bigpharma in pharmacogenomics 2005-2010
Figure 4: Pharmacogenomic partnering by deal type since 2005
Figure 5: Pharmacogenomic partnering by disease type since 2005
Figure 6: Pharmacogenomic partnering by oncology target since 2005
Figure 7: Pharmacogenomic deals with a headline value
Figure 8: Pharmacogenomic deal headline value distribution, US$million
Figure 9: Pharmacogenomic deal headline value distribution, US$million
Figure 10: Pharmacogenomic deals with upfront payment values
Figure 11: Pharmacogenomic deal upfront payment distribution, US$million
Figure 12: Pharmacogenomic deals with milestone payments
Figure 13: Pharmacogenomic deal milestone payment distribution, US$million
Figure 14: Pharmacogenomic deals with royalty rates, %
Figure 15: Pharmacogenomic deal royalty rate distribution, %
Figure 16: Top pharmacogenomic deals by value since 2005
Figure 17: Top pharmacogenomic deals signed by bigpharma value since 2005
Figure 18: Online partnering resources
Figure 19: Forthcoming partnering events
Figure 20: Deal type definitions
Figure 21: Pharmacogenomic partnering agreement between GlaxoSmithKline and Response
Genetics, May 2010

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