Liver Fibrosis Drugs Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 - 2025

Liver Fibrosis Drugs Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 - 2025

  • Transparency Market Research
  • Ongoing
  • Pharmaceutical

Report Description

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Liver fibrosis is the most common liver condition. It is the imbalance of decomposition and synthesis of the extra cellular matrix (ECM) and collagens caused by necrosis and liver cell inflammation. Cellular components primarily are fibroblastic cells, hepatic stellate cells (HSC), and mononuclear macrophages cells. Extra cellular matrix (ECM) is composed of glycoproteins, collagen, and protein-polysaccharides. Fibrosis is a process when connective tissue starts to proliferate in the portal area. In a normal liver, 5.5 mg to 6.5 mg of collagen can be found in every gram of liver tissue. Cirrhotic liver contains over 8.0 mg of collagen in every gram of liver tissue. It can also be higher than 20 mg. Liver fibrosis can be categorized into viral hepatitis fibrosis, parasitic infection fibrosis, alcoholic fibrosis, biliary fibrosis, intoxication fibrosis, cardiogenic fibrosis, and metabolic fibrosis. Immunologically, liver fibrosis can be categorized into passive fibrosis and active fibrosis. Viral hepatitis fibrosis is the most common form of liver fibrosis and is usually caused by chronic hepatitis C, B, and D. According to PubMed and scientific journal research, over 500 million people are affected by hepatitis B and C virus. Infected people develop chronic hepatitis, which leads to fibrosis. Liver fibrosis can cause major complications, including liver failure, portal hypertension, and liver cancer. The risk of liver cancer is greatly increased once fibrosis develops. Liver cancer is among the top ten causes of death globally. High alcohol consumption, fatty liver (steatosis), and insulin resistance increase the risk of liver fibrosis.

The global liver fibrosis drugs market is expanding significantly due to increase in prevalence of the disease. Long term medication also increases the incidence of liver fibrosis. Rise in funding by government and private sector for the treatment of liver fibrosis in terms of reimbursement is projected to drive the market during the forecast period. Low rate of voluntary screening for the disease is a major restraint of the market.

The global liver fibrosis drugs market can be segmented based on drug class, distribution channel, and region. In terms of drug class, the market can be categorized into interferon (IFN) therapy, nucleoside analogue, maloti lipid, and others.

Based on distribution channel, the global liver fibrosis drugs market can be classified into hospital pharmacies, retail pharmacies, and online pharmacies. In terms of revenue, the hospital pharmacies segment is projected to hold a significant share of the liver fibrosis drugs market in 2016.

In terms of region, the global liver fibrosis drugs market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is the leading market for liver fibrosis drugs. In terms of revenue, the U.S. holds a major share of the liver fibrosis drugs market in North America. The market in Europe is expanding rapidly due to increase in the patient population in the region, especially in the U.K. and Germany. The market in Asia Pacific and Latin America is projected to expand significantly in the near future. Developing economies such as China and India are anticipated to contribute to the growth of the market in Asia Pacific between 2017 and 2025, due to better health care infrastructure, economic growth, increase in the number of insurance payers, growth of the private health care sector, and increase in awareness among people in these countries.

Key players operating in the global liver fibrosis drugs market are Bristol-Myers Squibb Company, Gilead Sciences, Inc., Celgene Corporation, Pfizer, Inc., FibroGen, Inc., Pharmaxis Limited, Dicerna Pharmaceuticals, Inc., LG Life Science Ltd., and Dynavax Technologies Corporation.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market   

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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