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KOL Perspectives: Mid-to-Late Stage Pipeline Therapies in Lupus

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Published Date : Feb 2018

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No. of Pages : 39 Pages

KOL Perspectives: Mid-to-Late Stage Pipeline Therapies in Lupus


This KOL Insight briefing focuses on opinions of mid- to late-stage pipeline therapies in lupus.

The briefing includes analysis of KOL opinion on the following topic areas -
- Development of Lupuzor for SLE
- Lupuzors Phase III trial design
- Lupuzors Phase IIb efficacy data in SLE
- Anticipated future use of Lupuzor in SLE
- Development of baricitinib in SLE
- Endpoints used in baricitinibs Phase II trial
- Expectations for baricitinibs Phase II trial results
- Views on the increased risk of thromboembolic events seen with baricitinib in RA
- Views on the risk of thromboembolic events in the lupus patient population
- Concerns regarding herpes zoster in lupus patients
- Impact of high infection rate with JAK inhibitor use in RA, on anticipated baricitinib use in SLE
- Development of IFN kinoid in SLE
- IFN kinoid vs. anifrolumab in SLE

Key Highlights

- Most KOLs flagged the need for more data to understand Lupuzors mechanism of action and elucidate its efficacy in lupus patients
- KOLs were divided over Lupuzors efficacy in lupus based on its Phase IIb data, with some highlighting that it may be comparable to belimumab
- Most KOLs had a positive opinion regarding baricitinibs development in lupus, based on its data in other indications.


- The insight briefing is based on Sociable Pharmas analysis of primary research with our lupus key opinion leaders (KOLs)
- In total, we conducted interviews with 14 KOLs: Seven Europe-based & seven US-based
- Interviews performed in December 2017
- KOL data is analyzed to produce: Charts summarizing KOL opinions
- Chart call-outs of key information & details
- KOL quotes
- Summary of KOL reporting trends
- Insight from Sociable Pharma's analysts.

Reasons to buy

- Combines Qualitative & semi-quantitative insight from key opinion leaders on "Mid-to-Late Stage Pipeline Therapies in Lupus"
- Includes insight & recommendations from our disease-specific healthcare analysts
- Utilizes independent expert viewpoints to validate the impact of new clinical data & emerging trends on management of Lupus
- Provides cost-effective support for your advisory boards, with topics acting as a catalyst for further expert discussion.
Table of Contents
Executive Summary
Research Panel Composition
Results & Implications

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