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Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Pipeline Review, H2 2016

Published By :

Global Markets Direct

Published Date : Nov 2016

Category :

Pharmaceutical

No. of Pages : 40 Pages

Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Pipeline Review, H2 2016

Summary

Global Markets Directs, Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Pipeline Review, H2 2016, provides in depth analysis on Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted pipeline therapeutics.

The report provides comprehensive information on the Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted therapeutics development and features dormant and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note:
*Certain sections in the report may be removed or altered based on the availability and relevance of data.
*Updated report will be delivered in 48 hours of order confirmation.

Scope

- The report provides a snapshot of the global therapeutic landscape for Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46)
- The report reviews Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted therapeutics and enlists all their major and minor projects
- The report assesses Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and its most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
Introduction 5
Global Markets Direct Report Coverage 5
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) Overview 6
Therapeutics Development 7
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Products under Development by Stage of Development 7
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Products under Development by Therapy Area 8
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Products under Development by Indication 9
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Pipeline Products Glance 10
Late Stage Products 10
Early Stage Products 11
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Products under Development by Companies 12
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Therapeutics Assessment 14
Assessment by Monotherapy/Combination Products 14
Assessment by Mechanism of Action 15
Assessment by Route of Administration 16
Assessment by Molecule Type 18
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Companies Involved in Therapeutics Development 19
Nivalis Therapeutics, Inc. 19
Saje Pharma, LLC 20
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Drug Profiles 21
cavosonstat - Drug Profile 21
Product Description 21
Mechanism Of Action 21
R&D Progress 21
SPL-227.1 - Drug Profile 23
Product Description 23
Mechanism Of Action 23
R&D Progress 23
SPL-334 - Drug Profile 24
Product Description 24
Mechanism Of Action 24
R&D Progress 24
SPL-334.1 - Drug Profile 25
Product Description 25
Mechanism Of Action 25
R&D Progress 25
SPL-875.1 - Drug Profile 26
Product Description 26
Mechanism Of Action 26
R&D Progress 26
SPL-891.1 - Drug Profile 27
Product Description 27
Mechanism Of Action 27
R&D Progress 27
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Dormant Projects 28
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Discontinued Products 30
Formaldehyde Dehydrogenase (S Nitrosoglutathione Reductase or NAD Dependent Formaldehyde Dehydrogenase or EC 1.2.1.46) - Featured News & Press Releases 31
Jul 07, 2016: Nivalis Therapeutics Announces Completion of Enrollment in Phase 2 Study of N91115 for Treatment of Cystic Fibrosis 31
May 16, 2016: Nivalis Therapeutics Announces First Patient Dosed in Second Phase 2 Study of N91115 for Treatment of Cystic Fibrosis 31
Apr 05, 2016: Nivalis Therapeutics Reaches 50 Percent Enrollment Milestone in Phase 2 Clinical Trial in Cystic Fibrosis 32
Mar 07, 2016: Nivalis Therapeutics Expands N91115 Clinical Development Program in Cystic Fibrosis 32
Mar 01, 2016: Nivalis Therapeutics Announces Appointment of Paul Sekhri to Its Board of Directors 33
Feb 29, 2016: Nivalis Therapeutics Reports Fourth Quarter and Full-Year 2015 Financial Results 34
Feb 18, 2016: Nivalis Therapeutics Announces FDA Fast Track Designation for N91115 in Patients With Cystic Fibrosis 35
Jan 15, 2016: Nivalis Therapeutics Announces FDA Orphan Drug Designation for N91115 in Cystic Fibrosis 36
Dec 01, 2015: Nivalis Therapeutics Announces First Patient Dosed in Phase 2 Study of N91115 for Treatment of Cystic Fibrosis 36
Oct 07, 2015: Nivalis Therapeutics Announces Positive Phase 1b Results for N91115 in Patients With Cystic Fibrosis and Plans to Initiate Phase 2 Trial 37
Mar 14, 2014: N30 Pharmaceuticals Initiates Phase 1 Clinical Trial for Novel Cystic Fibrosis Therapy 38
Mar 12, 2014: N30 Announces Start of Oral Dosing of N91115 in a Phase 1 Clinical Trial 38
Appendix 39
Methodology 39
Coverage 39
Secondary Research 39
Primary Research 39
Expert Panel Validation 39
Contact Us 39
Disclaimer 40

List of Tables
Number of Products under Development for, H2 2016 7
Number of Products under Development by Therapy Area, H2 2016 8
Number of Products under Development by Indication, H2 2016 9
Comparative Analysis by Late Stage Development, H2 2016 10
Comparative Analysis by Early Stage Products, H2 2016 11
Number of Products under Development by Companies, H2 2016 12
Products under Development by Companies, H2 2016 13
Assessment by Monotherapy/Combination Products, H2 2016 14
Number of Products by Stage and Mechanism of Action, H2 2016 15
Number of Products by Stage and Route of Administration, H2 2016 17
Number of Products by Stage and Molecule Type, H2 2016 18
Pipeline by Nivalis Therapeutics, Inc., H2 2016 19
Pipeline by Saje Pharma, LLC, H2 2016 20
Dormant Projects, H2 2016 28
Dormant Projects (Contd..1), H2 2016 29
Discontinued Products, H2 2016 30

List of Figures
Number of Products under Development for, H2 2016 7
Number of Products under Development by Therapy Area, H2 2016 8
Number of Products under Development by Top 10 Indication, H2 2016 9
Assessment by Monotherapy/Combination Products, H2 2016 14
Number of Products by Stage and Mechanism of Actions, H2 2016 15
Number of Products by Routes of Administration, H2 2016 16
Number of Products by Stage and Routes of Administration, H2 2016 16
Number of Products by Stage and Molecule Type, H2 2016 18

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