Disintegrating Agents Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 - 2025

Disintegrating Agents Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 - 2025

  • Transparency Market Research
  • Ongoing
  • Chemicals

Report Description

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Disintegrating agents are chemical agents consisting of a mixture of substances or a single substance that are added to tablets and other encapsulated formulations to facilitate disintegration of the capsule or tablet into smaller remains for better discharge of the drug in the body. This process helps provide better results of the drug on the body.  Disintegrating agents primarily find application in the pharmaceutical industry. These agents are used in the preparation of tablets and other formulations. Disintegration plays a major role in facilitating drug activity. There are various stages or procedures based on which a disintegrating agent can be added to the drug formulation. Based on its procedure of adding, the process can have a profound influence on the effectiveness of the drug. When a disintegrating agent is added before the granulation process, it is known as intragranular. When it is added after granulation and before the compression process, it is called as extragranular. A disintegrating agent can also be added at both intragranular and extragranular stages.

Three mechanism involved in drug or tablet disintegration are swelling, wicking, and deformation. In the swelling mechanism, the product that is disintegrating agent impart the disintegrating effect through swelling. Starch is a type of disintegrating agent that shows this mechanism. The disintegrating agent that does not swell, exhibits disintegrating effect through wicking, i.e., through porosity and capillary action. Disintegrating agents with low cohesiveness and compressibility enhance porosity and provide pathways into the tablet or drug. In the deformation mechanism, the disintegrating agent is deformed or distorted under pressure during tableting. The deformation of the disintegrating agent helps improve the performance of the drug. There are other mechanisms involved in drug or tablet disintegration, such as enzymatic action, gas release, and exposure to heat.

Various types of disintegrating agents used in drug formulations include starch, cellulose, and polyvinylpyrrolidone. Starch was the first disintegrating agent that was widely used for tablet manufacturing. Potato starch and corn starch were the original type of starch used as a disintegrating agent. Microcrystalline cellulose is a type of cellulose that is widely used for flow and binding in drug formulations. It exhibits effective tablet disintegrant when used in a concentration ranging between 10% and 20%. Polyvinylpyrrolidone is another kind of disintegrating agent used in drug formulations. Other disintegrating agents used in drug formulations or tablets are alginates and ion-exchange resins. Superdisintegrants are a category of segment that shows faster disintegration. Rise in the demand for faster disintegrating formulations has increased the requirement for superdisintegrants across the globe. Superdisintegrants are effective at low concentration, have greater disintegrating efficiency, and are effective intragranularly. Examples of superdisintegrants include modified starches, modified celluloses, and cross-linked polyvinylpyrrolidone. However, superdisintegrants are hygroscopic; therefore, they are not used in moisture sensitive drugs.

Based upon region, the disintegrating agents market can be segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa. North America dominated the pharmaceutical or drug industry in 2016, followed by Europe and Asia Pacific region, as North America region consists of developed country such as the U.S., where demand for advanced drugs is higher. The demand for disintegrating agent in Asia Pacific region is projected to rise at a rapid rate during the forecast period. Growing pharmaceutical industry in developing countries such as China and India is projected to boost the market share in the region. The demand for disintegrating agents in Latin America and Middle East & Africa is observed to be less, however the share is anticipated to boost in the coming years due to growing need for advanced medical assistance.

Key players operating in the disintegrating agents market are The Dow Chemical Company, Air Liquide, Corel Pharma Chem, Sidley Chemical Co. Ltd., DFE Pharma, Fuji Chemical Industries Co. Ltd., Nippon Soda Co. Ltd. HPC and others.                

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market   

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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