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Colorectal Cancer Drug Development Pipeline Review, 2017

Published By :

GBI Research

Published Date : Sep 2017

Category :

Pharmaceutical

No. of Pages : 299 Pages

Colorectal Cancer Drug Development Pipeline Review, 2017

Summary

This report provides an overview of the colorectal cancer pipeline landscape. The report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for anal, rectal and colorectal cancer, and features dormant and discontinued projects.

Anal cancer starts in the anus. Symptoms include rectal bleeding, rectal itching, a lump or mass at the anal opening, pain or a feeling of fullness in the anal area, narrowing of stool, pain or a feeling of fullness in the anal area

Rectal cancer affects the lower part of the colon, which connects the large bowel to the anus. The common signs and symptoms of rectal cancer include a change in bowel habits, diarrhea, constipation, or feeling that the bowel does not empty completely, blood, either bright red or very dark in the stool, stools that are narrower than usual, general abdominal discomfort such as frequent gas pains, bloating, fullness or cramps, weight loss with no known reason, constant tiredness and vomiting.

Finally, colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancers begin as a growth called a polyp on the inner lining of the colon or rectum. Symptoms include abdominal pain and tenderness in the lower abdomen, blood in the stool, diarrhea, constipation, change in bowel habits, narrow stools and weight loss with no known reason.

The size of these pipelines ranges from 10 products in rectal cancer to 581 products in colorectal cancer. Across all three of these indications, however, kinases, immune-related proteins, DNA-related proteins and viral proteins are common targets, closely reflecting the current treatment landscape of these diseases.

Scope

- Which companies are the most active within the pipeline for colorectal cancer therapeutics?
- Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
- To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
- What are the most important R&D milestones and data publications to have happened in the field of colorectal cancer?

Reasons to buy

- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
- Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
- Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
- Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 5
1.2 List of Figures 10
2 Introduction 11
2.1 Colorectal Cancer Report Coverage 11
2.2 Anal Cancer - Overview 11
2.3 Rectal Cancer - Overview 11
2.4 Colorectal Cancer - Overview 11
3 Therapeutics Development 12
3.1 Anal Cancer 12
3.2 Rectal Cancer 16
3.3 Colorectal Cancer 18
4 Therapeutics Assessment 56
4.1 Anal Cancer 56
4.2 Rectal Cancer 63
4.3 Colorectal Cancer 71
5 Companies Involved in Therapeutics Development 100
5.1 Anal Cancer 100
5.2 Rectal Cancer 108
5.3 Colorectal Cancer 114
6 Dormant Projects 241
6.1 Anal Cancer 241
6.2 Rectal Cancer 241
6.3 Colorectal Cancer 242
7 Discontinued Products 261
7.1 Anal Cancer 261
7.2 Colorectal Cancer 261
8 Product Development Milestones 265
8.1 Anal Cancer 265
8.2 Rectal Cancer 278
8.3 Colorectal Cancer 280
9 Appendix 298
9.1 Methodology 298
9.2 Coverage 298
9.3 Secondary Research 298
9.4 Primary Research 298
9.5 Expert Panel Validation 298
9.6 Contact Us 299
9.7 Disclaimer 299

1.1 List of Tables
Table 1: Number of Products under Development for Anal Cancer 12
Table 2: Number of Products under Development by Companies Anal Cancer 14
Table 3: Products under Development by Companies Anal Cancer 15
Table 4: Number of Products under Development for Rectal Cancer 16
Table 5: Number of Products under Development by Companies Rectal Cancer 17
Table 6: Products under Development by Companies Rectal Cancer 18
Table 7: Number of Products under Development by Companies Colorectal Cancer 21
Table 8: Number of Products under Development by Universities/Institutes Colorectal Cancer 30
Table 9: Products under Development by Companies Colorectal Cancer 32
Table 10: Products under Development by Universities/Institutes Colorectal Cancer 52
Table 11: Number of Products by Stage and Target Anal Cancer 57
Table 12: Number of Products by Stage and Mechanism of Action Anal Cancer 59
Table 13: Number of Products by Stage and Route of Administration Anal Cancer 61
Table 14: Number of Products by Stage and Molecule Type Anal Cancer 63
Table 15: Number of Products by Stage and Target Rectal Cancer 65
Table 16: Number of Products by Stage and Mechanism of Action Rectal Cancer 67
Table 17: Number of Products by Stage and Route of Administration Rectal Cancer 69
Table 18: Number of Products by Stage and Molecule Type Rectal Cancer 71
Table 19: Number of Products by Stage and Target Colorectal Cancer 73
Table 20: Number of Products by Stage and Mechanism of Action Colorectal Cancer 87
Table 21: Number of Products by Stage and Route of Administration Colorectal Cancer 97
Table 22: Number of Products by Stage and Molecule Type Colorectal Cancer 99
Table 23: Anal Cancer - Pipeline by Advaxis Inc 100
Table 24: Anal Cancer - Pipeline by Amgen Inc 101
Table 25: Anal Cancer - Pipeline by Atara Biotherapeutics Inc 101
Table 26: Anal Cancer - Pipeline by Bayer AG 102
Table 27: Anal Cancer - Pipeline by BeiGene Ltd 102
Table 28: Anal Cancer - Pipeline by Eli Lilly and Company 103
Table 29: Anal Cancer - Pipeline by Immunovaccine Inc 103
Table 30: Anal Cancer - Pipeline by ISA Pharmaceuticals BV 104
Table 31: Anal Cancer - Pipeline by Merck & Co Inc 105
Table 32: Anal Cancer - Pipeline by Ono Pharmaceutical Co Ltd 106
Table 33: Anal Cancer - Pipeline by Oryx GmbH & Co KG 106
Table 34: Anal Cancer - Pipeline by PDS Biotechnology Corp 106
Table 35: Anal Cancer - Pipeline by Sun Pharma Advanced Research Company Ltd 107
Table 36: Anal Cancer - Pipeline by Taiwan Liposome Company Ltd 108
Table 37: Rectal Cancer - Pipeline by AbbVie Inc 108
Table 38: Rectal Cancer - Pipeline by Advaxis Inc 109
Table 39: Rectal Cancer - Pipeline by Eisai Co Ltd 109
Table 40: Rectal Cancer - Pipeline by GlaxoSmithKline Plc 110
Table 41: Rectal Cancer - Pipeline by Karyopharm Therapeutics Inc 111
Table 42: Rectal Cancer - Pipeline by Madrigal Pharmaceuticals Inc. 111
Table 43: Rectal Cancer - Pipeline by NewLink Genetics Corp 112
Table 44: Rectal Cancer - Pipeline by Peregrine Pharmaceuticals Inc 113
Table 45: Rectal Cancer - Pipeline by Regeneron Pharmaceuticals Inc 113
Table 46: Rectal Cancer - Pipeline by Taiwan Liposome Company Ltd 114
Table 47: Colorectal Cancer - Pipeline by 2cureX ApS 114
Table 48: Colorectal Cancer - Pipeline by 3-V Biosciences Inc 115
Table 49: Colorectal Cancer - Pipeline by 3SBio Inc 115
Table 50: Colorectal Cancer - Pipeline by 4SC AG 116
Table 51: Colorectal Cancer - Pipeline by AB Science SA 116
Table 52: Colorectal Cancer - Pipeline by AbbVie Inc 117
Table 53: Colorectal Cancer - Pipeline by AbGenomics International Inc 118
Table 54: Colorectal Cancer - Pipeline by Aclaris Therapeutics Inc 118
Table 55: Colorectal Cancer - Pipeline by Adamed Sp z oo 119
Table 56: Colorectal Cancer - Pipeline by Aduro BioTech Inc 119
Table 57: Colorectal Cancer - Pipeline by Advenchen Laboratories LLC 120
Table 58: Colorectal Cancer - Pipeline by Allinky Biopharma 120
Table 59: Colorectal Cancer - Pipeline by amcure GmbH 121
Table 60: Colorectal Cancer - Pipeline by Amgen Inc 121
Table 61: Colorectal Cancer - Pipeline by Antibe Therapeutics Inc 122
Table 62: Colorectal Cancer - Pipeline by APEIRON Biologics AG 122
Table 63: Colorectal Cancer - Pipeline by Apexigen Inc 123
Table 64: Colorectal Cancer - Pipeline by Aphios Corp 123
Table 65: Colorectal Cancer - Pipeline by Aposense Ltd 124
Table 66: Colorectal Cancer - Pipeline by ARMO Biosciences Inc 124
Table 67: Colorectal Cancer - Pipeline by ArQule Inc 125
Table 68: Colorectal Cancer - Pipeline by Array BioPharma Inc 125
Table 69: Colorectal Cancer - Pipeline by Asana BioSciences LLC 126
Table 70: Colorectal Cancer - Pipeline by Aslan Pharmaceuticals Pte Ltd 126
Table 71: Colorectal Cancer - Pipeline by Astellas Pharma Inc 127
Table 72: Colorectal Cancer - Pipeline by Astex Pharmaceuticals Inc 127
Table 73: Colorectal Cancer - Pipeline by AstraZeneca Plc 128
Table 74: Colorectal Cancer - Pipeline by Aurobindo Pharma Ltd 129
Table 75: Colorectal Cancer - Pipeline by AVEO Pharmaceuticals Inc 129
Table 76: Colorectal Cancer - Pipeline by B Cell Design SAS 130
Table 77: Colorectal Cancer - Pipeline by Basilea Pharmaceutica Ltd 130
Table 78: Colorectal Cancer - Pipeline by Bavarian Nordic A/S 131
Table 79: Colorectal Cancer - Pipeline by Bayer AG 132
Table 80: Colorectal Cancer - Pipeline by BeiGene Ltd 132
Table 81: Colorectal Cancer - Pipeline by Beijing Hanmi Pharmaceutical Co Ltd 133
Table 82: Colorectal Cancer - Pipeline by BeyondSpring Pharmaceuticals Inc 133
Table 83: Colorectal Cancer - Pipeline by Biocon Ltd 134
Table 84: Colorectal Cancer - Pipeline by Bionomics Ltd 134
Table 85: Colorectal Cancer - Pipeline by Bionovis SA 135
Table 86: Colorectal Cancer - Pipeline by Biotecnol Ltd 135
Table 87: Colorectal Cancer - Pipeline by Biothera Pharmaceutical Inc 136
Table 88: Colorectal Cancer - Pipeline by Boehringer Ingelheim GmbH 137
Table 89: Colorectal Cancer - Pipeline by Boston Biomedical Inc 137
Table 90: Colorectal Cancer - Pipeline by Bristol-Myers Squibb Company 138
Table 91: Colorectal Cancer - Pipeline by Calithera Biosciences Inc 138
Table 92: Colorectal Cancer - Pipeline by Cancer Prevention Pharmaceuticals Inc 139
Table 93: Colorectal Cancer - Pipeline by Cantargia AB 139
Table 94: Colorectal Cancer - Pipeline by Carna Biosciences Inc 140
Table 95: Colorectal Cancer - Pipeline by Cascadian Therapeutics Inc 141
Table 96: Colorectal Cancer - Pipeline by CBT Pharmaceuticals Inc 141
Table 97: Colorectal Cancer - Pipeline by CCRP Therapeutics GmbH 141
Table 98: Colorectal Cancer - Pipeline by Celgene Corp 142
Table 99: Colorectal Cancer - Pipeline by Celldex Therapeutics Inc 143
Table 100: Colorectal Cancer - Pipeline by Cellectar Biosciences Inc 143
Table 101: Colorectal Cancer - Pipeline by Celleron Therapeutics Ltd 144
Table 102: Colorectal Cancer - Pipeline by Celltrion Inc 144
Table 103: Colorectal Cancer - Pipeline by Celyad SA 145
Table 104: Colorectal Cancer - Pipeline by Chipscreen Biosciences Ltd 145
Table 105: Colorectal Cancer - Pipeline by ChoDang Pharm Co Ltd 146
Table 106: Colorectal Cancer - Pipeline by Chong Kun Dang Pharmaceutical Corp 146
Table 107: Colorectal Cancer - Pipeline by Cleave Biosciences Inc 147
Table 108: Colorectal Cancer - Pipeline by Cleveland BioLabs Inc 147
Table 109: Colorectal Cancer - Pipeline by COARE Biotechnology Inc 148
Table 110: Colorectal Cancer - Pipeline by Coherus BioSciences Inc 149
Table 111: Colorectal Cancer - Pipeline by Compugen Ltd 149
Table 112: Colorectal Cancer - Pipeline by Conatus Pharmaceuticals Inc 150
Table 113: Colorectal Cancer - Pipeline by Corvus Pharmaceuticals Inc 150
Table 114: Colorectal Cancer - Pipeline by Critical Outcome Technologies Inc 151
Table 115: Colorectal Cancer - Pipeline by CrystalGenomics Inc 151
Table 116: Colorectal Cancer - Pipeline by Daiichi Sankyo Company Ltd 152
Table 117: Colorectal Cancer - Pipeline by DanDrit Biotech A/S 152
Table 118: Colorectal Cancer - Pipeline by Deciphera Pharmaceuticals LLC 153
Table 119: Colorectal Cancer - Pipeline by Dr. Reddy's Laboratories Ltd 153
Table 120: Colorectal Cancer - Pipeline by eFFECTOR Therapeutics Inc 154
Table 121: Colorectal Cancer - Pipeline by Eisai Co Ltd 154
Table 122: Colorectal Cancer - Pipeline by Eli Lilly and Co 155
Table 123: Colorectal Cancer - Pipeline by Endor Nanotechnologies SL 155
Table 124: Colorectal Cancer - Pipeline by Ensol Biosciences Inc 156
Table 125: Colorectal Cancer - Pipeline by EntreChem SL 156
Table 126: Colorectal Cancer - Pipeline by Enzene Biosciences Ltd 157
Table 127: Colorectal Cancer - Pipeline by Enzo Biochem Inc 157
Table 128: Colorectal Cancer - Pipeline by EpiThany Inc 158
Table 129: Colorectal Cancer - Pipeline by Etubics Corp 158
Table 130: Colorectal Cancer - Pipeline by Exelixis Inc 159
Table 131: Colorectal Cancer - Pipeline by Exicure Inc 159
Table 132: Colorectal Cancer - Pipeline by F-star Biotechnology Ltd 160
Table 133: Colorectal Cancer - Pipeline by F. Hoffmann-La Roche Ltd 160
Table 134: Colorectal Cancer - Pipeline by Formosa Laboratories Inc 161
Table 135: Colorectal Cancer - Pipeline by Forty Seven Inc 161
Table 136: Colorectal Cancer - Pipeline by Fusion Antibodies Ltd 162
Table 137: Colorectal Cancer - Pipeline by Gene Techno Science Co Ltd 162
Table 138: Colorectal Cancer - Pipeline by Genentech Inc 163
Table 139: Colorectal Cancer - Pipeline by Genor BioPharma Co Ltd 163
Table 140: Colorectal Cancer - Pipeline by Genoscience Pharma 164
Table 141: Colorectal Cancer - Pipeline by Genzyme Corp 164
Table 142: Colorectal Cancer - Pipeline by Gilead Sciences Inc 165
Table 143: Colorectal Cancer - Pipeline by GlaxoSmithKline Plc 166
Table 144: Colorectal Cancer - Pipeline by Glenmark Pharmaceuticals Ltd 166
Table 145: Colorectal Cancer - Pipeline by Glycostem Therapeutics BV 167
Table 146: Colorectal Cancer - Pipeline by Glycotope GmbH 167
Table 147: Colorectal Cancer - Pipeline by Green Cross Corp 168
Table 148: Colorectal Cancer - Pipeline by Handok Inc 168
Table 149: Colorectal Cancer - Pipeline by Hanmi Pharmaceuticals Co Ltd 169
Table 150: Colorectal Cancer - Pipeline by Heat Biologics Inc 169
Table 151: Colorectal Cancer - Pipeline by Hemispherx Biopharma Inc 170
Table 152: Colorectal Cancer - Pipeline by Humanigen Inc 170
Table 153: Colorectal Cancer - Pipeline by Humorigin Biotechnology Corp 171
Table 154: Colorectal Cancer - Pipeline by Hutchison MediPharma Ltd 171
Table 155: Colorectal Cancer - Pipeline by iDD biotech SAS 172
Table 156: Colorectal Cancer - Pipeline by Ideaya Biosciences Inc 172
Table 157: Colorectal Cancer - Pipeline by Ignyta Inc 172
Table 158: Colorectal Cancer - Pipeline by Ildong Pharmaceutical Co Ltd 173
Table 159: Colorectal Cancer - Pipeline by Immodulon Therapeutics Ltd 173
Table 160: Colorectal Cancer - Pipeline by ImmuneXcite Inc 174
Table 161: Colorectal Cancer - Pipeline by Immunomedics Inc 175
Table 162: Colorectal Cancer - Pipeline by Immunovative Therapies Ltd 175
Table 163: Colorectal Cancer - Pipeline by Incanthera Ltd 176
Table 164: Colorectal Cancer - Pipeline by Incyte Corp 176
Table 165: Colorectal Cancer - Pipeline by Innovation Pharmaceuticals Inc 177
Table 166: Colorectal Cancer - Pipeline by Innovent Biologics Inc 177
Table 167: Colorectal Cancer - Pipeline by Inovio Pharmaceuticals Inc 178
Table 168: Colorectal Cancer - Pipeline by Interprotein Corp 178
Table 169: Colorectal Cancer - Pipeline by Intezyne Technologies Inc 179
Table 170: Colorectal Cancer - Pipeline by Ionis Pharmaceuticals Inc 179
Table 171: Colorectal Cancer - Pipeline by Isofol Medical AB 180
Table 172: Colorectal Cancer - Pipeline by Jeil Pharmaceutical Co Ltd 180
Table 173: Colorectal Cancer - Pipeline by JHL Biotech Inc 181
Table 174: Colorectal Cancer - Pipeline by Jiangsu Hengrui Medicine Co Ltd 182
Table 175: Colorectal Cancer - Pipeline by Johnson & Johnson 182
Table 176: Colorectal Cancer - Pipeline by Kancera AB 183
Table 177: Colorectal Cancer - Pipeline by Karyopharm Therapeutics Inc 183
Table 178: Colorectal Cancer - Pipeline by Kura Oncology Inc 184
Table 179: Colorectal Cancer - Pipeline by Laboratorio ELEA SACIF y A 184
Table 180: Colorectal Cancer - Pipeline by LipoMedix Pharmaceutical Inc 185
Table 181: Colorectal Cancer - Pipeline by Loxo Oncology Inc 185
Table 182: Colorectal Cancer - Pipeline by Luye Pharma Group Ltd 186
Table 183: Colorectal Cancer - Pipeline by Mabion SA 187
Table 184: Colorectal Cancer - Pipeline by MacroGenics Inc 187
Table 185: Colorectal Cancer - Pipeline by Mantis Therapeutics BV 188
Table 186: Colorectal Cancer - Pipeline by Marina Biotech Inc 188
Table 187: Colorectal Cancer - Pipeline by Medesis Pharma SA 189
Table 188: Colorectal Cancer - Pipeline by MediaPharma SRL 189
Table 189: Colorectal Cancer - Pipeline by MedImmune LLC 189
Table 190: Colorectal Cancer - Pipeline by Medinet Co Ltd 190
Table 191: Colorectal Cancer - Pipeline by Medivir AB 191
Table 192: Colorectal Cancer - Pipeline by Merck & Co Inc 191
Table 193: Colorectal Cancer - Pipeline by Merck KGaA 192
Table 194: Colorectal Cancer - Pipeline by Merrimack Pharmaceuticals Inc 193
Table 195: Colorectal Cancer - Pipeline by Merus NV 193
Table 196: Colorectal Cancer - Pipeline by Microlin Bio Inc 194
Table 197: Colorectal Cancer - Pipeline by Millennium Pharmaceuticals Inc 194
Table 198: Colorectal Cancer - Pipeline by Molecular Partners AG 195
Table 199: Colorectal Cancer - Pipeline by MolMed SpA 195
Table 200: Colorectal Cancer - Pipeline by Mologen AG 196
Table 201: Colorectal Cancer - Pipeline by Morphotek Inc 196
Table 202: Colorectal Cancer - Pipeline by Multimmune GmbH 197
Table 203: Colorectal Cancer - Pipeline by Mycenax Biotech Inc 197
Table 204: Colorectal Cancer - Pipeline by NantKwest Inc 198
Table 205: Colorectal Cancer - Pipeline by Natco Pharma Ltd 198
Table 206: Colorectal Cancer - Pipeline by NatureWise Biotech & Medicals Corp 199
Table 207: Colorectal Cancer - Pipeline by Nektar Therapeutics 200
Table 208: Colorectal Cancer - Pipeline by Neovacs SA 200
Table 209: Colorectal Cancer - Pipeline by Nerviano Medical Sciences Srl 201
Table 210: Colorectal Cancer - Pipeline by Nippon Kayaku Co Ltd 201
Table 211: Colorectal Cancer - Pipeline by NormOxys Inc 202
Table 212: Colorectal Cancer - Pipeline by Northwest Biotherapeutics Inc 202
Table 213: Colorectal Cancer - Pipeline by Novartis AG 203
Table 214: Colorectal Cancer - Pipeline by Novogen Ltd 204
Table 215: Colorectal Cancer - Pipeline by Noxxon Pharma AG 204
Table 216: Colorectal Cancer - Pipeline by NuCana BioMed Ltd 205
Table 217: Colorectal Cancer - Pipeline by OBI Pharma Inc 205
Table 218: Colorectal Cancer - Pipeline by Omnitura Therapeutics Inc 205
Table 219: Colorectal Cancer - Pipeline by Oncobiologics Inc 206
Table 220: Colorectal Cancer - Pipeline by Oncology Research International Ltd 206
Table 221: Colorectal Cancer - Pipeline by Oncolytics Biotech Inc 207
Table 222: Colorectal Cancer - Pipeline by OncoMed Pharmaceuticals Inc 208
Table 223: Colorectal Cancer - Pipeline by Onconova Therapeutics Inc 208
Table 224: Colorectal Cancer - Pipeline by Ono Pharmaceutical Co Ltd 209
Table 225: Colorectal Cancer - Pipeline by Oryx GmbH & Co KG 209
Table 226: Colorectal Cancer - Pipeline by Otsuka Holdings Co Ltd 210
Table 227: Colorectal Cancer - Pipeline by Oxford BioMedica Plc 210
Table 228: Colorectal Cancer - Pipeline by Pfizer Inc 211
Table 229: Colorectal Cancer - Pipeline by Pharma Mar SA 212
Table 230: Colorectal Cancer - Pipeline by PharmAbcine Inc 212
Table 231: Colorectal Cancer - Pipeline by Pivotal BioSciences Inc 212
Table 232: Colorectal Cancer - Pipeline by PlantForm Corp 213
Table 233: Colorectal Cancer - Pipeline by Plexxikon Inc 213
Table 234: Colorectal Cancer - Pipeline by PLx Pharma Inc 214
Table 235: Colorectal Cancer - Pipeline by Precision Biologics Inc 214
Table 236: Colorectal Cancer - Pipeline by Propanac Biopharma Inc 214
Table 237: Colorectal Cancer - Pipeline by Provectus Biopharmaceuticals Inc 215
Table 238: Colorectal Cancer - Pipeline by PsiOxus Therapeutics Ltd 216
Table 239: Colorectal Cancer - Pipeline by Puma Biotechnology Inc 216
Table 240: Colorectal Cancer - Pipeline by Puretech Health plc 217
Table 241: Colorectal Cancer - Pipeline by R Pharm 217
Table 242: Colorectal Cancer - Pipeline by Rafael Pharmaceuticals Inc 217
Table 243: Colorectal Cancer - Pipeline by RedHill Biopharma Ltd 218
Table 244: Colorectal Cancer - Pipeline by Redx Pharma Plc 218
Table 245: Colorectal Cancer - Pipeline by Rexahn Pharmaceuticals Inc 219
Table 246: Colorectal Cancer - Pipeline by Rgenix Inc 219
Table 247: Colorectal Cancer - Pipeline by Rhizen Pharmaceuticals SA 220
Table 248: Colorectal Cancer - Pipeline by Richter Gedeon Nyrt 220
Table 249: Colorectal Cancer - Pipeline by Samumed LLC 221
Table 250: Colorectal Cancer - Pipeline by Sanofi 221
Table 251: Colorectal Cancer - Pipeline by Selvita SA 222
Table 252: Colorectal Cancer - Pipeline by Siamab Therapeutics Inc 222
Table 253: Colorectal Cancer - Pipeline by Sichuan Kelun Pharmaceutical Co Ltd 223
Table 254: Colorectal Cancer - Pipeline by Sigma-Tau SpA 223
Table 255: Colorectal Cancer - Pipeline by Sigmoid Pharma Ltd 224
Table 256: Colorectal Cancer - Pipeline by Sillajen Biotherapeutics 224
Table 257: Colorectal Cancer - Pipeline by Simcere Pharmaceutical Group 225
Table 258: Colorectal Cancer - Pipeline by Sorrento Therapeutics Inc 225
Table 259: Colorectal Cancer - Pipeline by Steba Biotech SA 226
Table 260: Colorectal Cancer - Pipeline by Sumitomo Dainippon Pharma Co Ltd 226
Table 261: Colorectal Cancer - Pipeline by SuviCa Inc 227
Table 262: Colorectal Cancer - Pipeline by Symphogen A/S 227
Table 263: Colorectal Cancer - Pipeline by SynDevRx Inc 228
Table 264: Colorectal Cancer - Pipeline by Synermore Biologics Co Ltd 228
Table 265: Colorectal Cancer - Pipeline by Taiho Pharmaceutical Co Ltd 228
Table 266: Colorectal Cancer - Pipeline by TaiwanJ Pharmaceuticals Co Ltd 229
Table 267: Colorectal Cancer - Pipeline by Takeda Pharmaceutical Co Ltd 230
Table 268: Colorectal Cancer - Pipeline by Targovax ASA 230
Table 269: Colorectal Cancer - Pipeline by Tarrex Biopharma Ltd 231
Table 270: Colorectal Cancer - Pipeline by Tarveda Therapeutics Inc 231
Table 271: Colorectal Cancer - Pipeline by tella Inc 232
Table 272: Colorectal Cancer - Pipeline by Tiltan Pharma Ltd 232
Table 273: Colorectal Cancer - Pipeline by Tocagen Inc 232
Table 274: Colorectal Cancer - Pipeline by TRACON Pharmaceuticals Inc 233
Table 275: Colorectal Cancer - Pipeline by Transgene SA 233
Table 276: Colorectal Cancer - Pipeline by United BioPharma Inc 234
Table 277: Colorectal Cancer - Pipeline by Vaccinex Inc 234
Table 278: Colorectal Cancer - Pipeline by VasGene Therapeutics Inc 235
Table 279: Colorectal Cancer - Pipeline by Vaximm AG 235
Table 280: Colorectal Cancer - Pipeline by ViiV Healthcare Ltd 235
Table 281: Colorectal Cancer - Pipeline by Vitality Biopharma Inc 236
Table 282: Colorectal Cancer - Pipeline by Wellstat Biologics Corp 236
Table 283: Colorectal Cancer - Pipeline by Wilex AG 237
Table 284: Colorectal Cancer - Pipeline by WntResearch AB 237
Table 285: Colorectal Cancer - Pipeline by Wuhan YZY Biopharma Co Ltd 238
Table 286: Colorectal Cancer - Pipeline by XBiotech Inc 238
Table 287: Colorectal Cancer - Pipeline by XuanZhu Pharma Co Ltd 239
Table 288: Colorectal Cancer - Pipeline by Yabao Pharmaceutical Group Co Ltd 239
Table 289: Colorectal Cancer - Pipeline by Zymeworks Inc 240
Table 290: Anal Cancer - Dormant Projects 241
Table 291: Rectal Cancer - Dormant Projects 241
Table 292: Colorectal Cancer - Dormant Projects 242
Table 293: Anal Cancer - Discontinued Products 261
Table 294: Colorectal Cancer - Discontinued Products 261


1.2 List of Figures
Figure 1: Number of Products under Development for Anal Cancer 12
Figure 2: Number of Products under Development by Companies Anal Cancer 13
Figure 3: Number of Products under Development for Rectal Cancer 16
Figure 4: Number of Products under Development by Companies Rectal Cancer 17
Figure 5: Number of Products under Development for Colorectal Cancer 18
Figure 6: Number of Products under Development by Companies Colorectal Cancer 20
Figure 7: Number of Products under Development by Universities/Institutes Colorectal Cancer 30
Figure 8: Number of Products by Top 10 Targets Anal Cancer 56
Figure 9: Number of Products by Stage and Top 10 Targets Anal Cancer 56
Figure 10: Number of Products by Top 10 Mechanism of Actions Anal Cancer 58
Figure 11: Number of Products by Stage and Top 10 Mechanism of Actions Anal Cancer 58
Figure 12: Number of Products by Routes of Administration Anal Cancer 60
Figure 13: Number of Products by Stage and Routes of Administration Anal Cancer 60
Figure 14: Number of Products by Molecule Types Anal Cancer 62
Figure 15: Number of Products by Stage and Molecule Types Anal Cancer 62
Figure 16: Number of Products by Top 10 Targets Rectal Cancer 63
Figure 17: Number of Products by Stage and Top 10 Targets Rectal Cancer 64
Figure 18: Number of Products by Top 10 Mechanism of Actions Rectal Cancer 66
Figure 19: Number of Products by Stage and Top 10 Mechanism of Actions Rectal Cancer 66
Figure 20: Number of Products by Routes of Administration Rectal Cancer 68
Figure 21: Number of Products by Stage and Routes of Administration Rectal Cancer 68
Figure 22: Number of Products by Molecule Types Rectal Cancer 70
Figure 23: Number of Products by Stage and Molecule Types Rectal Cancer 70
Figure 24: Number of Products by Top 10 Targets Colorectal Cancer 71
Figure 25: Number of Products by Stage and Top 10 Targets Colorectal Cancer 72
Figure 26: Number of Products by Top 10 Mechanism of Actions Colorectal Cancer 86
Figure 27: Number of Products by Stage and Top 10 Mechanism of Actions Colorectal Cancer 86
Figure 28: Number of Products by Routes of Administration Colorectal Cancer 96
Figure 29: Number of Products by Stage and Routes of Administration Colorectal Cancer 96
Figure 30: Number of Products by Top 10 Molecule Types Colorectal Cancer 98
Figure 31: Number of Products by Stage and Top 10 Molecule Types Colorectal Cancer 98

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