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Cancer-Testis Antigen 1 (Autoimmunogenic Cancer-Testis Antigen NY-ESO-1 or Cancer-Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Pipeline Review, H1 2016

Published By :

Global Markets Direct

Published Date : Jun 2016

Category :

Cancer

No. of Pages : 79 Pages

Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Pipeline Review, H1 2016

Summary

Global Markets Directs, Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Pipeline Review, H1 2016, provides in depth analysis on Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted pipeline therapeutics.

The report provides comprehensive information on the Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted therapeutics development and features dormant and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A)
- The report reviews Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted therapeutics and enlists all their major and minor projects
- The report assesses Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and its most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) Overview 8
Cancer/Testis Antigen 1 is a protein encoded by CTAG1A gene is an antigen that is over expressed in many cancers but that is also expressed in normal ovary and testis tissues which makes it a good candidate for a cancer vaccine. Therapeutics Development 8
Therapeutics Development 9
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Products under Development by Stage of Development 9
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Products under Development by Therapy Area 10
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Products under Development by Indication 11
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Pipeline Products Glance 13
Late Stage Products 13
Early Stage Products 14
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Products under Development by Companies 15
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Products under Development by Universities/Institutes 19
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Therapeutics Assessment 21
Assessment by Monotherapy/Combination Products 21
Assessment by Mechanism of Action 22
Assessment by Route of Administration 23
Assessment by Molecule Type 25
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Companies Involved in Therapeutics Development 27
Aduro BioTech, Inc. 27
Boehringer Ingelheim GmbH 28
Celldex Therapeutics, Inc. 29
GlaxoSmithKline Plc 31
Immune Design Corp. 32
ImmunoFrontier, Inc. 33
Kite Pharma, Inc. 34
Sanofi Pasteur SA 35
Scancell Holdings Plc 36
Vault Pharma Inc. 37
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Drug Profiles 38
ADU-623 - Drug Profile 38
Product Description 38
Mechanism Of Action 38
R&D Progress 38
BI-1361849 - Drug Profile 39
Product Description 39
Mechanism Of Action 39
R&D Progress 39
CDX-1401 - Drug Profile 41
Product Description 41
Mechanism Of Action 41
R&D Progress 41
Cellular Immunotherapy to Inhibit NY ESO-1 for Oncology - Drug Profile 44
Product Description 44
Mechanism Of Action 44
R&D Progress 44
Cellular Immunotherapy to Target MAGE-A1, MAGE-A3 and NY-ESO-1 for Oncology - Drug Profile 46
Product Description 46
Mechanism Of Action 46
R&D Progress 46
CMB-305 - Drug Profile 47
Product Description 47
Mechanism Of Action 47
R&D Progress 47
G-305 - Drug Profile 50
Product Description 50
Mechanism Of Action 50
R&D Progress 50
GSK-2241658A - Drug Profile 52
Product Description 52
Mechanism Of Action 52
R&D Progress 52
IMF-001 - Drug Profile 53
Product Description 53
Mechanism Of Action 53
R&D Progress 53
IMM-65 - Drug Profile 54
Product Description 54
Mechanism Of Action 54
R&D Progress 54
LV-305 - Drug Profile 55
Product Description 55
Mechanism Of Action 55
R&D Progress 55
SCIB-2 - Drug Profile 57
Product Description 57
Mechanism Of Action 57
R&D Progress 57
Vaccine for Acute Myeloid Leukemia and Myelodysplastic Syndrome - Drug Profile 58
Product Description 58
Mechanism Of Action 58
R&D Progress 58
VCP-2292 - Drug Profile 59
Product Description 59
Mechanism Of Action 59
R&D Progress 59
VPI-111 - Drug Profile 60
Product Description 60
Mechanism Of Action 60
R&D Progress 60
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Dormant Projects 61
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Discontinued Products 64
Cancer/Testis Antigen 1 (Autoimmunogenic Cancer/Testis Antigen NY-ESO-1 or Cancer/Testis Antigen 6.1 or L Antigen Family Member 2 or CTAG1A) - Featured News & Press Releases 65
Jun 08, 2016: Immune Design Announces Updated Results For Its Immuno-oncology Product Candidate LV305 at ASCO 65
Jun 08, 2016: Immune Design Announces Updated Results For Immuno-oncology Product Candidate CMB305 At ASCO 66
Jun 04, 2016: Celldex Therapeutics' CDX-1401, CDX-301 Combination Generates Potent NY-ESO-1 Immune Responses in Patients with Melanoma 66
Apr 21, 2016: Immune Design Announces Presentation on LV-305 at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting 67
Apr 18, 2016: Celldex Therapeutics Presents Poster on CDX-1401 at the AACR Annual Meeting 2016 68
Feb 09, 2016: Immune Design Announces Positive Topline Data From Phase 1 Clinical Trial of CMB305 68
Jan 08, 2016: Immune Design Receives Orphan Drug Designation From the U.S. FDA for Complementary Components of CMB305 69
Nov 11, 2015: Immune Design Announces Start of Randomized Phase 2 Cancer Immunotherapy Combination Trial in Patients With Soft Tissue Sarcoma 70
Aug 12, 2015: Immune Design Announces Phase 2 Cancer Immunotherapy Trial Collaboration 70
Jun 01, 2015: Aduro Biotech Announces ASCO Presentation of Encouraging Data From Ongoing Phase 1b Clinical Trial of Its Immunotherapy for the Treatment of Mesothelioma 71
May 13, 2015: Immune Design Announces Positive Data from Phase 1 Studies On LV305 at the 2015 American Society of Clinical Oncology Annual Meeting 72
May 13, 2015: Immune Design To Present Positive Phase 1 Data From On G305 at the 2015 American Society of Clinical Oncology Annual Meeting 74
Mar 31, 2015: Immune Design Announces Positive Topline Data From Phase 1 Clinical Trials of Immuno-Oncology CMB305 Agent 75
Mar 26, 2015: Immune Design Announces Treatment of Patients With CMB305 Investigational Immuno-Oncology Agent 76
Jun 05, 2014: Immune Design Announces Treatment of First Patient in Phase 1 Clinical Trial of LV305 Immuno-Oncology Agent 77
Appendix 78
Methodology 78
Coverage 78
Secondary Research 78
Primary Research 78
Expert Panel Validation 78
Contact Us 78
Disclaimer 79

List of Tables
Number of Products under Development for, H1 2016 9
Number of Products under Development by Therapy Area, H1 2016 10
Number of Products under Development by Indication, H1 2016 11
Comparative Analysis by Late Stage Development, H1 2016 13
Comparative Analysis by Early Stage Products, H1 2016 14
Number of Products under Development by Companies, H1 2016 15
Products under Development by Companies, H1 2016 16
Products under Development by Companies, H1 2016 (Contd..1) 17
Products under Development by Companies, H1 2016 (Contd..2) 18
Number of Products under Investigation by Universities/Institutes, H1 2016 19
Products under Investigation by Universities/Institutes, H1 2016 20
Assessment by Monotherapy/Combination Products, H1 2016 21
Number of Products by Stage and Mechanism of Action, H1 2016 22
Number of Products by Stage and Route of Administration, H1 2016 24
Number of Products by Stage and Molecule Type, H1 2016 26
Pipeline by Aduro BioTech, Inc., H1 2016 27
Pipeline by Boehringer Ingelheim GmbH, H1 2016 28
Pipeline by Celldex Therapeutics, Inc., H1 2016 29
Pipeline by GlaxoSmithKline Plc, H1 2016 31
Pipeline by Immune Design Corp., H1 2016 32
Pipeline by ImmunoFrontier, Inc., H1 2016 33
Pipeline by Kite Pharma, Inc., H1 2016 34
Pipeline by Sanofi Pasteur SA, H1 2016 35
Pipeline by Scancell Holdings Plc, H1 2016 36
Pipeline by Vault Pharma Inc., H1 2016 37
Dormant Projects, H1 2016 61
Dormant Projects (Contd..1), H1 2016 62
Dormant Projects (Contd..2), H1 2016 63
Discontinued Products, H1 2016 64

List of Figures
Number of Products under Development for, H1 2016 9
Number of Products under Development by Therapy Area, H1 2016 10
Number of Products under Development by Top 10 Indication, H1 2016 11
Comparative Analysis by Early Stage Products, H1 2016 14
Assessment by Monotherapy/Combination Products, H1 2016 21
Number of Products by Stage and Mechanism of Actions, H1 2016 22
Number of Products by Routes of Administration, H1 2016 23
Number of Products by Stage and Routes of Administration, H1 2016 23
Number of Products by Molecule Types, H1 2016 25
Number of Products by Stage and Molecule Type, H1 2016 25

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