Biliary Atresia Treatment Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 - 2025

Biliary Atresia Treatment Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017 - 2025

  • Transparency Market Research
  • Ongoing
  • Healthcare IT

Report Description


Biliary atresia or extra hepatic ductopenia is an acquired disease of the liver. This disease is characterized by the obliteration of the extra hepatic biliary system which results in obstruction of the bile flow from the liver to gall bladder. This can lead to damage to the liver or liver cirrhosis and can become fatal if not treated at an early stage. It occurs because biliary ducts are not normally developed in infants. Currently, there is no known cause of biliary atresia. However, various studies suggest that Reovirus 3 infection, congenital cytomegalovirus infection, and congenital malformation might be responsible for causing biliary atresia in humans. Some of the symptoms associated with biliary atresia are pale or clay-colored stool, jaundice, dark urine, slow or no weight gain, mild hepatomegaly, and enlarged spleen. The treatment regimen widely used to treat biliary atresia can be medications including bile acids, glucocorticoids and antibiotics, and surgical procedure. The most common treatment is a surgical operation called Kasai procedure (connects liver to the intestine for the flow of bile) which is successful if performed before the baby is eight weeks old. However, a liver transplant may or may not be needed depending on the future condition of the baby. The three forms of biliary atresia are: type I or perinatal biliary atresia, type II or biliary atresia splenic malformation, and type III or cystic biliary atresia.

Rise in incidence of biliary atresia is the primary factor contributing to the growth of the biliary atresia treatment market. Moreover, other factors such as high demand for safe and effective pharmacological therapies fuel the growth of the market. Furthermore, increasing patient population and introduction of innovative products are expected to drive the untapped biliary atresia treatment market. However, rise in overall health care expenditure and safety concerns are the major factors likely to hamper the growth of the biliary atresia treatment market in the near future.

The global biliary atresia treatment market can be segmented based on type of treatment. In terms of type of treatment, the market can be sub-segmented into medication and surgery. Medications can be categorized into bile acids such as ursodiol, glucocorticoids such as methylprednisolone and antibiotics such as trimethoprim-sulfamethoxazole. Surgical procedure involved in the treatment of biliary atresia is Kasai hepatoportoenterostomy (HPE).

Geographically, the global biliary atresia treatment market can be segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Asia Pacific is the largest market for biliary atresia treatment products owing to high incidence and prevalence rates of biliary atresia. Various studies conducted on biliary atresia suggests that the overall incidence rate of biliary atresia in countries in Asia is 1 per 8,000 live births. Moreover, it is more common in infants in China as compared to those in Japan. However, the overall incidence rate of biliary atresia in the U.S. is 1 per 10,000 to 15,000 live births, while it is approximately 1 in 12,000 births in Europe.

Key companies and research institutes engaged in the development of biliary atresia treatment are AstraZeneca plc, Daiichi Sankyo Company Ltd., Eisai Co. Ltd., Johnson & Johnson Services Inc., Novartis International AG, Pfizer, Inc., the University of Pennsylvania, and the University of Texas.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market 

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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