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Inhibition of Glucagon Might be Key to Treatment of Diabetes

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Published on : Apr 19, 2016

Sedentary lifestyle and change in food habits have led to obesity and diabetes across the globe. Increased consumption of fast food and sugary aerated drinks among younger population has led to the growing prevalence of diabetes among population under the age of 25. According to the World Health Organization, an approximate 9% among adults aged 18 years and above suffered from diabetes in 2014. By 2030, the disease is projected to be the seventh leading cause of death across the globe. The growing demand for various diagnostic devices such as glucose monitors and medications for treatment of diabetes has propelled the growth of the global diabetes market. Extensive research and development activities have introduced several niche and specialized products for diabetes. However, the overall diabetes market has registered a slight decline in the last couple of years owing to weak reimbursement policies. 

Potential New Diabetes Treatment Might Offer Double Advantages

A recent study has pointed out an innovative way to treat diabetes by blocking the hormone that raises sugar levels in blood. The research findings in mice, as published in eLife, suggests that the inhibition of hormone glucagon can be explored as an alternative to insulin injection. However, this has its own limitations. According to the researchers at the University of Geneva, the human body requires some residual insulin production to trigger blocking of glucagon. Other studies have also pointed out that the disease is caused by increased level of glucagon rather than the deficiency of insulin. By blocking glucagon, excessive high glucose level in blood can be prevented even when insulin is lacking completely. The usage of insulin therapy and inhibition of glucagon as a combined treatment might be effective and safe to treat diabetes.