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Arthritis is an inflammation of one joint or more than one joint. The main symptoms of arthritis include joint pain and stiffness with different causes and treatment methods. Osteoarthritis and rheumatoid arthritis are the most common types of arthritis.

People of all ages, races, and sexes can have arthritis and is the major cause of disability in America. The symptoms of arthritis may come and go. They may stay in the same state for years, but may get worse over time. Acute arthritis leads to chronic pain, difficulty in walking or climbing stairs, and inability to do daily activities.

The burden of rheumatoid arthritis is considerable on healthcare systems across the world. It impairs quality of life of patients and at least 50% patients are unable to maintain full-time employment within 10 years of onset of the condition. Both developed and developing countries present lucrative opportunities for sales of drugs for rheumatoid arthritis.