34-Diaminodiphenylmethane, also known as 3, 4’-Methylenedioxyamphetamine is an entactogen, empathogen-, and psychostimulant. 34-Diaminodiphenylmethane is commonly known as ‘sass’. It is a psychedelic drug belonging to the amphetamine family. In pharmacology, 34-Diaminodiphenylmethane acts as a serotonin-norepinephrine-dopamine releasing agent or SNDRA. It is a controlled substance in most of the countries and its unregistered sale and possession is deemed illegal. 34-Diaminodiphenylmethane can be administered orally, through insufflation, sublingually, and intravenously. It is rarely sought after for recreational purposes as compared to the other drugs belonging to the amphetamine family. However, it is an important material used in the production of MDMA, also known as ‘ecstasy’.
34-Diaminodiphenylmethane is synthesized from essential oils such as piperonal and safrole. Since it is synthesized from safrone oil, the compound or its consumable product is also known as ‘Sally’. It is also known as ?-Methyl-3, 4-methylenedioxy-?-phenyl ethylamine, 1-(1, 3-Benzodioxol-5-yl)-2-propanamine, 4-[(3-aMinophenyl) Methyl] aniline, and 1-(3, 4-Methylenedioxyphenyl)-2-propanamine. Its molecular formula is C13H14N2. In chemical form, 34-Diaminodiphenylmethane is categorized as an ‘irritant’. It is harmful if swallowed and causes serious skin and eye irritation if safety protocols are not followed. It can also cause respiratory irritation even from a single exposure.
MDA or 34-Diaminodiphenylmethane produces serotonergic neurotoxic effects activated by the initial metabolism of the compound. It also activates a response of neuroglia, the non-neural brain cells in spine and brain that do not produce electrical impulses but maintain homeostasis and provide protection and support for the neurons. This active response wears off after the use of 34-Diaminodiphenylmethane. A number of researchers have explored the use of 34-Diaminodiphenylmethane in psychotherapy. 34-Diaminodiphenylmethane was described in initial research phases, as a unique psychedelic drug with an unusually strong emotional component. It is also known on the street as the ‘love drug’ due to its psychedelic effects that employ secretion of serotonin and dopamine to provide the user with feeling of happiness, love, and ecstasy.
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