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Urinary Incontinence - Pipeline Review, H1 2015

Published By :

Global Markets Direct

Published Date : Jan 2015

Category :

Diseases & Conditions

No. of Pages : 66 Pages


Global Markets Directs, Urinary Incontinence Pipeline Review, H1 2015, provides an overview of the Urinary Incontinences therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Urinary Incontinence, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Urinary Incontinence and special features on late-stage and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Scope

  • The report provides a snapshot of the global therapeutic landscape of Urinary Incontinence
  • The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in the therapeutics development for Urinary Incontinence and enlists all their major and minor projects
  • The report summarizes all the dormant and discontinued pipeline projects 
  • A review of the Urinary Incontinence products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • A detailed assessment of monotherapy and combination therapy pipeline projects
  • Coverage of the Urinary Incontinence pipeline on the basis of target, MoA, route of administration and molecule type
  • Latest news and deals relating related to pipeline products

Reasons to buy

  • Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Identify and understand important and diverse types of therapeutics under development for Urinary Incontinence
  • Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
  • Devise corrective measures for pipeline projects by understanding Urinary Incontinence pipeline depth and focus of Indication therapeutics
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents 2
List of Tables 5
List of Figures 6

Introduction 7
Global Markets Direct Report Coverage 7
Urinary Incontinence Overview 8
Therapeutics Development 9
Pipeline Products for Urinary Incontinence - Overview 9
Pipeline Products for Urinary Incontinence - Comparative Analysis 10
Urinary Incontinence - Therapeutics under Development by Companies 11
Urinary Incontinence - Therapeutics under Investigation by Universities/Institutes 12
Urinary Incontinence - Pipeline Products Glance 13
Late Stage Products 13
Clinical Stage Products 14
Early Stage Products 15
Urinary Incontinence - Products under Development by Companies 16
Urinary Incontinence - Products under Investigation by Universities/Institutes 17
Urinary Incontinence - Companies Involved in Therapeutics Development 18
Allergan, Inc. 18
Astellas Pharma Inc. 19
Beech Tree Labs, Inc. 20
Cook MyoSite Incorporated 21
Evotec AG 22
FemmePharma Global Healthcare, Inc. 23
Innovacell Biotechnologie AG 24
Recordati S.p.A. 25
TheraVida, Inc. 26
Urinary Incontinence - Therapeutics Assessment 27
Assessment by Monotherapy Products 27
Assessment by Combination Products 28
Assessment by Target 29
Assessment by Mechanism of Action 31
Assessment by Route of Administration 33
Assessment by Molecule Type 35
Drug Profiles 37
(mirabegron + solifenacin succinate) - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
(tolterodine + pilocarpine) - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
BTL-ui - Drug Profile 40
Product Description 40
Mechanism of Action 40
R&D Progress 40
Cell Therapy for Urinary Incontinence - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
ICES-13 - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
oxybutynin hydrochloride - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
Prof-003 - Drug Profile 44
Product Description 44
Mechanism of Action 44
R&D Progress 44
REC-1819 - Drug Profile 45
Product Description 45
Mechanism of Action 45
R&D Progress 45
senrebotase - Drug Profile 46
Product Description 46
Mechanism of Action 46
R&D Progress 46
Small Molecule to Antagonize P2X3 and P2X2/3 for Inflammatory Pain, Neuropathic Pain and Urinary Incontinence - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
Stem Cell Therapy for CAD, Urinary Incontinence and Fecal Incontinence - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
THVD-202 - Drug Profile 50
Product Description 50
Mechanism of Action 50
R&D Progress 50
Urinary Incontinence - Recent Pipeline Updates 51
Urinary Incontinence - Dormant Projects 54
Urinary Incontinence - Discontinued Products 57
Urinary Incontinence - Product Development Milestones 59
Featured News & Press Releases 59
Jul 03, 2013: Impax Laboratories Confirms Patent Challenge Relating to Generic TOVIAZ 4 mg and 8 mg 59
Jan 03, 2013: TheraVida Announces Positive Top-line Phase II Results For Tolenix In Patients With Overactive Bladder And Urge Urinary Incontinence 59
Nov 06, 2012: Beech Tree Labs Completes Phase IIa Urinary Incontinence Clinical Trial Using UISH001 60
Mar 15, 2012: Innovacell To Present Phase IIb Trial Results Of ICES13 At MedTech Investing Europe Conference 60
Dec 05, 2011: Pfizer’s Toviaz Shows Positive Top-Line Primary Endpoint Result In Study Of Overactive Bladder In Vulnerable Elderly Patients 61
Nov 08, 2011: Pfizer Announces Positive Top-Line Primary Endpoint Results Of Toviaz In Overactive Bladder Including Nocturnal Urinary Urgency 61
Aug 30, 2011: Innovacell passes a further milestone 62
May 16, 2011: TheraVida Initiates Phase II Trial Of THVD-201 For Overactive Bladder And Urinary Incontinence 63
Apr 13, 2011: Beech Tree Labs Initiates Urinary Incontinence Trial 63
Mar 22, 2011: TheraVida Announces Positive Results From Phase I Trial Of THVD-201 64

Appendix 65
Methodology 65
Coverage 65
Secondary Research 65
Primary Research 65
Expert Panel Validation 65
Contact Us 65
Disclaimer 66

List of Table


Number of Products under Development for Urinary Incontinence, H1 2015 9
Number of Products under Development for Urinary Incontinence - Comparative Analysis, H1 2015 10
Number of Products under Development by Companies, H1 2015 11
Number of Products under Investigation by Universities/Institutes, H1 2015 12
Comparative Analysis by Late Stage Development, H1 2015 13
Comparative Analysis by Clinical Stage Development, H1 2015 14
Comparative Analysis by Early Stage Development, H1 2015 15
Products under Development by Companies, H1 2015 16
Products under Investigation by Universities/Institutes, H1 2015 17
Urinary Incontinence - Pipeline by Allergan, Inc., H1 2015 18
Urinary Incontinence - Pipeline by Astellas Pharma Inc., H1 2015 19
Urinary Incontinence - Pipeline by Beech Tree Labs, Inc., H1 2015 20
Urinary Incontinence - Pipeline by Cook MyoSite Incorporated, H1 2015 21
Urinary Incontinence - Pipeline by Evotec AG, H1 2015 22
Urinary Incontinence - Pipeline by FemmePharma Global Healthcare, Inc., H1 2015 23
Urinary Incontinence - Pipeline by Innovacell Biotechnologie AG, H1 2015 24
Urinary Incontinence - Pipeline by Recordati S.p.A., H1 2015 25
Urinary Incontinence - Pipeline by TheraVida, Inc., H1 2015 26
Assessment by Monotherapy Products, H1 2015 27
Assessment by Combination Products, H1 2015 28
Number of Products by Stage and Target, H1 2015 30
Number of Products by Stage and Mechanism of Action, H1 2015 32
Number of Products by Stage and Route of Administration, H1 2015 34
Number of Products by Stage and Molecule Type, H1 2015 36
Urinary Incontinence Therapeutics - Recent Pipeline Updates, H1 2015 51
Urinary Incontinence - Dormant Projects, H1 2015 54
Urinary Incontinence - Dormant Projects (Contd..1), H1 2015 55
Urinary Incontinence - Dormant Projects (Contd..2), H1 2015 56
Urinary Incontinence - Discontinued Products, H1 2015 57
Urinary Incontinence - Discontinued Products (Contd..1), H1 2015 58

List of Chart


Number of Products under Development for Urinary Incontinence, H1 2015 9
Number of Products under Development for Urinary Incontinence - Comparative Analysis, H1 2015 10
Number of Products under Development by Companies, H1 2015 11
Comparative Analysis by Clinical Stage Development, H1 2015 14
Assessment by Monotherapy Products, H1 2015 27
Assessment by Combination Products, H1 2015 28
Number of Products by Top 10 Targets, H1 2015 29
Number of Products by Stage and Top 10 Targets, H1 2015 30
Number of Products by Top 10 Mechanism of Actions, H1 2015 31
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 32
Number of Products by Top 10 Routes of Administration, H1 2015 33
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 34
Number of Products by Top 10 Molecule Types, H1 2015 35
Number of Products by Stage and Top 10 Molecule Types, H1 2015 36

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