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Bone Morphogenetic Proteins Market (Types: rhBMP-2 and rhbmp-7; Applications: Spinal Fusion, Trauma, Reconstructive and Oral - Maxillofacial) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2014 - 2022

Published By :

Transparency

Published Date : Apr 2015

Category :

Biotechnology

No. of Pages : 65 Pages

 

Bone morphogenetic proteins (BMP) are naturally occurring proteins found in the human body. Identified in 1965 by Marshall Urist, bone morphogenetic proteins are among the most potent growth factors that induce mesenchymal stem cells to differentiate into osteoblast cells. Twenty different types of BMPs have been discovered to date; only BMP 2, 7 and 9 have osteoinductive property and have been proven to play a significant role in bone formation. However, of these, only BMP-2 and BMP-7 are commercially available. These proteins trigger intracellular signal pathways by binding to the receptor of the mesenchymal stem cells resulting in transformation of stem cells into tissue specific progenitor cells. These cells are involved in the synthesis of musculoskeletal tissue formation, extracellular growth and matrix.

 

The bone morphogenetic proteins market report studies the current scenario as well as future market potential for bone morphogenetic proteins globally. The market overview section of the report comprises qualitative analysis of the overall bone morphogenetic proteins market considering the factors determining the market dynamics such as drivers, restraints and opportunities, along with Porter’s Five Forces analysis and market attractiveness analysis. In addition, various analyses such as event regulatory scenario and value chain analysis have also been provided. Value chain analysis includes the study of major steps involved in the recombinant bone morphogenetic proteins preparation and distribution. Regulatory scenario includes the study of different regulatory norms and procedures that regulate the approval and commercialization of recombinant bone morphogenetic proteins products.

 

The global bone morphogenetic proteins market has been segmented based on type, application and geography. Based on type, the global BMP market has been categorized into recombinant bone morphogenetic protein-2 (rhBMP-2) and recombinant bone morphogenetic protein-7 (rhBMP-7). Based on application, the bone morphogenetic proteins market has been classified into spinal fusion, trauma, reconstructive and oral maxillofacial surgery. The market for these types and applications has been extensively analyzed on the basis of factors such as product approval date, product demand, sales revenue, geographic presence and product features. The market size and forecast in terms of revenue (USD million) for each of these segments have been provided for the period from 2012 to 2022, considering 2013 and 2014 as the base years. The report also provides the compound annual growth rate (CAGR) for each segment for the forecast period from 2014 to 2022.

 

Geographically, the BMP market has been classified into four major regions: North America, Europe, Asia-Pacific and Rest of the World (RoW). The market size and forecast for each region have been provided for the period from 2012 to 2022, in terms of types and applications, along with the CAGR (%) for the forecast period from 2014 to 2022. 

 

The bone morphogenetic proteins market report also provides a section on the competitive landscape, wherein the market share analysis of leading players in the global bone morphogenetic proteins market in terms of percentage share in 2013 has been discussed. A list of recommendations has also been included for new entrants as well as existing market players to help them establish a strong presence in the market and increase their market shares. The report concludes with the profiles of major players in the global bone morphogenetic proteins market such as Medtronic plc, Stryker Corporation and Cellumed Co. Ltd. The major market players are evaluated on various parameters such as company overview, financial overview, product portfolio, business strategies and recent developments.

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The global bone morphogenetic proteins market is segmented as follows:

 

Global Bone Morphogenetic Proteins Market Revenue, by Types

  • rhBMP-2 
  • rhBMP-7

Global Bone Morphogenetic Proteins Market Revenue, by Application

  • Spinal Fusion
  • Trauma
  • Reconstructive Surgery
  • Oral-Maxillofacial

Global Bone Morphogenetic Proteins Market Revenue, by Geography

  • North America
  • Types
  • Applications
  • Europe
  • Types
  • Applications
  • Asia Pacific
  • Types
  • Applications
  • RoW
  • Types
  • Applications

 

Chapter 1 Introduction

1.1 Report Description

1.2 Market Segmentation

1.3 Research Methodology

1.3.1 Secondary Research

1.3.2 Primary Research

1.4 Assumptions

 

Chapter 2 Executive Summary

2.1 Market Snapshot: Global Bone Morphogenetic Proteins Market (2013 & 2022)

2.2 Global Bone Morphogenetic Proteins Market Revenue, by Types, 2013 (USD Million)

2.3 Global Bone Morphogenetic Proteins Market Revenue, by Applications, 2013 (USD Million)

2.4 Comparative Analysis: Global Bone Morphogenetic Proteins Market Revenue, by Geography, 2013 & 2022 (Value %)

 

Chapter 3 Market Overview

3.1 Overview

3.2 Market Drivers

3.2.1 Increase in number of spinal fusion surgeries would expedite the demand of BMPs

3.2.2 Aging population likely to trigger the demand for bone morphogenetic proteins

3.2.3 Surge in trauma and sports related injuries

3.2.4 Increasing prevalence of lower back pain would increase the number of spinal surgeries

3.2.5 Rising demand for minimally invasive surgeries

3.3 Market Restraints

3.3.1 Off-label usage linked with serious side effects leads to decline in market revenue

3.3.2 Availability of alternative bone graft substitutes reduces the demand of BMPs

3.3.3 High cost of BMPs and approval for limited indications limits the market earning

3.4 Market Opportunities

3.4.1 Emerging countries

3.5 Porter’s Five Force Analysis: Global Bone Morphogenetic Proteins Market

3.5.1 Bargaining power of suppliers

3.5.2 Bargaining power of buyers

3.5.3 Threat of new entrants

3.5.4 Threat of substitutes

3.5.5 Competitive rivalry

3.6 Market Attractiveness Analysis: Global Bone Morphogenetic Proteins Market, by Geography, 2013

3.7 Regulatory Framework

3.8 Value Chain Analysis

3.9 Competitive Landscape

3.9.1 Global Bone Morphogenetic Proteins Market Share Analysis, by Key Players, 2013 (Value %)

3.10 Global Orthobiologics Market Revenue, by Types, 2012 – 2022 (USD Million)

 

Chapter 4 Bone Morphogenetic Proteins Market, by Types

4.1 Overview

4.1.1 Global Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

4.2 Average Pricing Analysis

4.3 Recombinant human bone morphogenetic protein-2 (rhBMP-2)

4.3.1 Global rhBMP-2 Market Revenue, 2012 – 2022 (USD Million)

4.4 Recombinant human bone morphogenetic protein-7 (rhBMP-7)

4.4.1 Global rhBMP-7 Market Revenue, 2012 – 2014 (USD Million)

 

Chapter 5 Bone Morphogenetic Proteins Market, by Application

5.1 Overview

5.1.1 Global Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

5.2 Spinal Fusion

5.2.1 Global Spinal Fusion Market Revenue,2012–2022 (USD Million)

5.3 Trauma

5.3.1 Global Trauma Market Revenue,2012–2022 (USD Million)

5.4 Reconstructive Surgery

5.4.1 Global Reconstructive Surgery Market Revenue,2012–2022 (USD Million)

5.5 Oral-Maxillofacial

5.5.1 Global Oral-Maxillofacial Market Revenue,2012–2022 (USD Million)

 

Chapter 6 Bone Morphogenetic Proteins Market, by Geography

6.1 Overview

6.1.1 Global Bone Morphogenetic Proteins Market Revenue, by Geography, 2012 – 2022 (USD Million)

6.2 North America

6.2.1 North America Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

6.2.2 North America Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

6.3 Europe

6.3.1 Europe Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

6.3.2 Europe Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

6.4 Asia-Pacific

6.4.1 Asia-Pacific Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

6.4.2 Asia-Pacific Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

6.5 Rest of the World

6.5.1 RoW Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

6.5.2 RoW Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

 

Chapter 7 Recommendation

7.1 Success strategies

7.1.1 Introduction of new indication, carriers and formulations for BMP products

7.1.2 Investing in emerging economies

 

Chapter 8 Company Profiles

8.1 Cellumed Co, Ltd.

8.1.1 Company Overview

8.1.2 Financial Overview

8.1.3 Product Portfolio

8.1.4 Business Strategies

8.1.5 Recent Developments

8.2 Medtronic plc

8.2.1 Company Overview

8.2.2 Financial Overview

8.2.3 Product Portfolio

8.2.4 Business Strategies

8.2.5 Recent Developments

8.3 Stryker Corporation

8.3.1 Company Overview

8.3.2 Financial Overview

8.3.3 Product Portfolio

8.3.4 Business Strategies

8.3.5 Recent Developments

List of Table

 

TABLE 1 Market Snapshot: Global Bone Morphogenetic Proteins Market (2013 & 2022)

TABLE 2 Global Orthobiologics Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 3 Global Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 4 Global Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

TABLE 5 Global Bone Morphogenetic Proteins Market Revenue, by Geography, 2012 – 2022 (USD Million)

TABLE 6 North America Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 7 North America Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

TABLE 8 Europe Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 9 Europe Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

TABLE 10 Asia-Pacific Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 11 Asia-Pacific Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million)

TABLE 12 RoW Bone Morphogenetic Proteins Market Revenue, by Types, 2012 – 2022 (USD Million)

TABLE 13 RoW  Bone Morphogenetic Proteins Market Revenue, by Applications, 2012 – 2022 (USD Million

List of Chart

 

FIG. 1 Bone Morphogenetic Proteins: Market Segmentation

FIG. 2 Global Bone Morphogenetic Proteins Market, by Types, 2013 (USD Million)

FIG. 3 Global Bone Morphogenetic Proteins Market, by Applications, 2013 (USD Million)

FIG. 4 Comparative Analysis: Global Bone Morphogenetic Proteins Revenue, by Geography, 2013 & 2022 (Value %)

FIG. 5 Porter’s Five Force Analysis: Global Bone Morphogenetic Proteins Market

FIG. 6 Market Attractiveness Analysis: Global Bone Morphogenetic Proteins Market, by Geography

FIG. 7 Value Chain: Global Bone Morphogenetic Proteins Market

FIG. 8 Global Bone Morphogenetic Protein Market Share Analysis, by Key Players, 2013 (Value %)

FIG. 9 Global rhBMP-2 Market Revenue, 2012 - 2022 (USD Million)

FIG. 10 Global rhBMP-7 Market Revenue, 2012 - 2014 (USD Million)

FIG. 11 Global Spinal Fusion Market Revenue, 2012 – 2022 (USD Million)

FIG. 12 Global Trauma Market Revenue, 2012 – 2022 (USD Million)

FIG. 13 Global Reconstructive Surgery Market Revenue, 2012 – 2022 (USD Million)

FIG. 14 Global Oral-Maxillofacial Market Revenue, 2012 – 2022 (USD Million)

FIG. 15 Medtronic, Inc.: Annual Revenue, 2012 - 2014 (USD Million)

FIG. 16 Stryker Corporation: Annual Revenue, 2012– 2014 (USD Million)

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