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Published on : Aug 09, 2016

It’s been known that seasonal allergies can turn out to be very inconvenient and to add to it, as per a recent study, the long-term impacts of these allergies are even worse. According to a new research, these seasonal allergens are capable of altering the brains in mice in such ways that were complicated to comprehend. The study also stated that the mice brain that were exposed to allergens such as grass pollens produced increased count of neurons within the hippocampus, an area of the brain that makes new memories. 

Allergic Reaction Resulted in Microglia Deactivation in Mice

This study has further put a question on how these allergies could pose a threat to the memory. Furthermore, the similar allergic reaction also resulted in microglia deactivation, which are the immune cells of the brain. This finding alarmed the team as other studies have demonstrated a reverse effect on these immune cells post bacterial infection.

Allergy Reaction Could be a Regulatory Mechanism for Protecting Hippocampus

For the purpose of study, which has now been published in the journal ‘Frontiers in Cellular Neuroscience’, the researchers have divided the mice into 2 groups i.e allergy controls and models and have exposed each of them to an allergen. This study explained a number of reactions apart from the deactivation of the hippocampus of the mice. For instance, it being a regulatory mechanism utilized for the protection of hippocampus, which plays a primary role in a number of significant processes, from the response of the immune system.

Rise in Hippocampus Neurons to Highly Impact Long Term Memory

It was also found that the rise in hippocampus neurons can also highly impact the long term memory as well as learning capabilities. As of now, there are a number of questions to which there are no answers, still this study was able to provide key highlights on the link between the brain and the immune system. 

The researchers also stated that the reaction of immune system within the body varies in case of bacterial infection v/s allergic reaction. They also stated that this study also depicted that the impact on the brain is directly dependent on the kind of immune reaction that takes place in the body.